Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA048185-07S1
Application #
2092947
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1988-09-01
Project End
1997-01-31
Budget Start
1995-03-15
Budget End
1996-01-31
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

White, C M; Martin, B K; Lee, L F et al. (1998) Effects of paclitaxel on cytokine synthesis by unprimed human monocytes, T lymphocytes, and breast cancer cells. Cancer Immunol Immunother 46:104-12
Lee, L F; Haskill, J S; Mukaida, N et al. (1997) Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter. Mol Cell Biol 17:5097-105
Chin, K C; Li, G; Ting, J P (1997) Activation and transdominant suppression of MHC class II and HLA-DMB promoters by a series of C-terminal class II transactivator deletion mutants. J Immunol 159:2789-94
Armstrong, T D; Clements, V K; Martin, B K et al. (1997) Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity. Proc Natl Acad Sci U S A 94:6886-91
Chin, K C; Li, G G; Ting, J P (1997) Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants. Proc Natl Acad Sci U S A 94:2501-6
Sundseth, R; MacDonald, G; Ting, J et al. (1997) DNA elements recognizing NF-Y and Sp1 regulate the human multidrug-resistance gene promoter. Mol Pharmacol 51:963-71
Lee, L F; Schuerer-Maly, C C; Lofquist, A K et al. (1996) Taxol-dependent transcriptional activation of IL-8 expression in a subset of human ovarian cancer. Cancer Res 56:1303-8
Wright, K L; Moore, T L; Vilen, B J et al. (1995) Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y. J Biol Chem 270:20978-86
Wright, K L; White, L C; Kelly, A et al. (1995) Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. J Exp Med 181:1459-71
MacDonald, G H; Itoh-Lindstrom, Y; Ting, J P (1995) The transcriptional regulatory protein, YB-1, promotes single-stranded regions in the DRA promoter. J Biol Chem 270:3527-33

Showing the most recent 10 out of 30 publications