Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA050329-06
Application #
2093709
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1989-07-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Biology
Type
Other Domestic Higher Education
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Lewis, Thera C; Prywes, Ron (2013) Serum regulation of Id1 expression by a BMP pathway and BMP responsive element. Biochim Biophys Acta 1829:1147-59
Muehlich, S; Hampl, V; Khalid, S et al. (2012) The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1. Oncogene 31:3913-23
Lee, Seung-Min; Vasishtha, Mansi; Prywes, Ron (2010) Activation and repression of cellular immediate early genes by serum response factor cofactors. J Biol Chem 285:22036-49
Muehlich, Susanne; Wang, Ruigong; Lee, Seung-Min et al. (2008) Serum-induced phosphorylation of the serum response factor coactivator MKL1 by the extracellular signal-regulated kinase 1/2 pathway inhibits its nuclear localization. Mol Cell Biol 28:6302-13
Shen, Jingshi; Snapp, Erik L; Lippincott-Schwartz, Jennifer et al. (2005) Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response. Mol Cell Biol 25:921-32
Selvaraj, Ahalya; Prywes, Ron (2004) Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependent. BMC Mol Biol 5:13
Shen, Jingshi; Prywes, Ron (2004) Dependence of site-2 protease cleavage of ATF6 on prior site-1 protease digestion is determined by the size of the luminal domain of ATF6. J Biol Chem 279:43046-51
Selvaraj, Ahalya; Prywes, Ron (2003) Megakaryoblastic leukemia-1/2, a transcriptional co-activator of serum response factor, is required for skeletal myogenic differentiation. J Biol Chem 278:41977-87
Cen, Bo; Selvaraj, Ahalya; Burgess, Rebecca C et al. (2003) Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes. Mol Cell Biol 23:6597-608
Chen, Xi; Shen, Jingshi; Prywes, Ron (2002) The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi. J Biol Chem 277:13045-52

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