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Bass, Phillip D; Gubler, Daniel A; Judd, Ted C et al. (2013) Mitomycinoid alkaloids: mechanism of action, biosynthesis, total syntheses, and synthetic approaches. Chem Rev 113:6816-63
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Williams, Robert M (2011) Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism. J Org Chem 76:4221-59
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Williams, Robert M; Stille, J; Echavarren, A et al. (2011) Discussion Addendum for: 4-Methoxy-4'-nitrophenyl. Recent Advances in the Stille Biaryl Coupling Reaction and Applications in Complex Natural Products Synthesis. Organic Synth 88:197-201
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Subramanian, Vidya; Williams, Robert M; Boger, Dale L et al. (2010) Methods to characterize the effect of DNA-modifying compounds on nucleosomal DNA. Methods Mol Biol 613:173-92
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Chamberland, Stephen; Grüschow, Sabine; Sherman, David H et al. (2009) Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C. Org Lett 11:791-4
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Gubler, Daniel A; Williams, Robert M (2009) Synthetic Studies Towards the Mitomycins: Construction of the Tetracyclic Core via a Reductive Aminocyclization Reaction. Tetrahedron Lett 50:4265-4267
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Namiki, Hidenori; Chamberland, Stephen; Gubler, Daniel A et al. (2007) Synthetic and biosynthetic studies on FR900482 and mitomycin C: an efficient and stereoselective hydroxymethylation of an advanced benzazocane intermediate. Org Lett 9:5341-4
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Subramanian, Vidya; Ducept, Pascal; Williams, Robert M et al. (2007) Effects of photochemically activated alkylating agents of the FR900482 family on chromatin. Chem Biol 14:553-63
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Judd, Ted C; Williams, Robert M (2004) A concise total synthesis of (+)-FR900482 and (+)-FR66979. J Org Chem 69:2825-30
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Williams, Robert M; Ducept, Pascal (2003) Interstrand cross-linking of DNA by FK317 and its deacetylated metabolites FR70496 and FR157471. Biochemistry 42:14696-701
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Showing the most recent 10 out of 15 publications
