Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA052098-02S2
Application #
3196867
Study Section
Virology Study Section (VR)
Project Start
1990-12-01
Project End
1993-11-30
Budget Start
1992-09-01
Budget End
1992-11-30
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Hawaii
Department
Type
Organized Research Units
DUNS #
121911077
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Kopanic, Jennifer L; Schlingmann, Barbara; Koval, Michael et al. (2015) Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75). Biochem J 466:571-85
Su, Vivian; Lau, Alan F (2014) Connexins: mechanisms regulating protein levels and intercellular communication. FEBS Lett 588:1212-20
Su, Vivian; Hoang, Christina; Geerts, Dirk et al. (2014) CIP75 (connexin43-interacting protein of 75 kDa) mediates the endoplasmic reticulum dislocation of connexin43. Biochem J 458:57-67
Cochrane, Kimberly; Su, Vivian; Lau, Alan F (2013) The connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane. Cell Commun Adhes 20:53-66
Su, Vivian; Cochrane, Kimberly; Lau, Alan F (2012) Degradation of connexins through the proteasomal, endolysosomal and phagolysosomal pathways. J Membr Biol 245:389-400
Su, Vivian; Lau, Alan F (2012) Ubiquitination, intracellular trafficking, and degradation of connexins. Arch Biochem Biophys 524:16-22
Dunn, Clarence A; Su, Vivian; Lau, Alan F et al. (2012) Activation of Akt, not connexin 43 protein ubiquitination, regulates gap junction stability. J Biol Chem 287:2600-7
Su, Vivian; Nakagawa, Reid; Koval, Michael et al. (2010) Ubiquitin-independent proteasomal degradation of endoplasmic reticulum-localized connexin43 mediated by CIP75. J Biol Chem 285:40979-90
Kieken, Fabien; Spagnol, Gaƫlle; Su, Vivian et al. (2010) NMR structure note: UBA domain of CIP75. J Biomol NMR 46:245-50
Cochrane, Kimberly; Berestecky, John M; Kitamura, Carolynn et al. (2009) Monoclonal antibodies against the connexin43-interacting protein CIP85. Hybridoma (Larchmt) 28:355-61

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