Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA052879-06S1
Application #
2095062
Study Section
Pathology B Study Section (PTHB)
Project Start
1990-07-19
Project End
1997-06-30
Budget Start
1994-07-01
Budget End
1997-06-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
La Jolla Institute
Department
Type
DUNS #
941462285
City
San Diego
State
CA
Country
United States
Zip Code
92121
Borgstrom, P; Bourdon, M A; Hillan, K J et al. (1998) Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo. Prostate 35:1-10
Deryugina, E I; Bourdon, M A; Reisfeld, R A et al. (1998) Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2. Cancer Res 58:3743-50
Deryugina, E I; Bourdon, M A; Luo, G X et al. (1997) Matrix metalloproteinase-2 activation modulates glioma cell migration. J Cell Sci 110 ( Pt 19):2473-82
Deryugina, E I; Luo, G X; Reisfeld, R A et al. (1997) Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2. Anticancer Res 17:3201-10
Schwabe, M; Deryugina, E I; Bosco, M C et al. (1996) IL-6 signals inhibition of cell adhesion in melanoma A375-C6. Anticancer Res 16:3363-70
Deryugina, E I; Bourdon, M A (1996) Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin. J Cell Sci 109 ( Pt 3):643-52
Deryugina, E I; Strongin, A; Yu, C et al. (1996) A novel monoclonal antibody, L1A3, is directed to the functional site of the alpha v integrin subunit. Hybridoma 15:279-88
Deryugina, E I; Ratnikov, B I; Bourdon, M A et al. (1995) Identification of a growth factor for primary murine stroma as macrophage colony-stimulating factor. Blood 86:2568-78
Torres Filho, I P; Hartley-Asp, B; Borgstrom, P (1995) Quantitative angiogenesis in a syngeneic tumor spheroid model. Microvasc Res 49:212-26
Sriramarao, P; Mendler, M; Bourdon, M A (1993) Endothelial cell attachment and spreading on human tenascin is mediated by alpha 2 beta 1 and alpha v beta 3 integrins. J Cell Sci 105 ( Pt 4):1001-12

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