Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA053717-03S1
Application #
3198382
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1990-12-21
Project End
1994-03-31
Budget Start
1992-12-01
Budget End
1994-03-31
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
Organized Research Units
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Georgakoudi, Irene; Feld, Michael S (2004) The combined use of fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in Barrett's esophagus. Gastrointest Endosc Clin N Am 14:519-37, ix
Georgakoudi, Irene; Van Dam, Jacques (2003) Characterization of dysplastic tissue morphology and biochemistry in Barrett's esophagus using diffuse reflectance and light scattering spectroscopy. Gastrointest Endosc Clin N Am 13:297-308
Georgakoudi, Irene; Jacobson, Brian C; Muller, Markus G et al. (2002) NAD(P)H and collagen as in vivo quantitative fluorescent biomarkers of epithelial precancerous changes. Cancer Res 62:682-7
Georgakoudi, I; Jacobson, B C; Van Dam, J et al. (2001) Fluorescence, reflectance, and light-scattering spectroscopy for evaluating dysplasia in patients with Barrett's esophagus. Gastroenterology 120:1620-9
Gurjar, R S; Backman, V; Perelman, L T et al. (2001) Imaging human epithelial properties with polarized light-scattering spectroscopy. Nat Med 7:1245-8
Wallace, M B; Perelman, L T; Backman, V et al. (2000) Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy. Gastroenterology 119:677-82
Wang, T D; Crawford, J M; Feld, M S et al. (1999) In vivo identification of colonic dysplasia using fluorescence endoscopic imaging. Gastrointest Endosc 49:447-55
Boustany, N N; Crawford, J M; Manoharan, R et al. (1999) Analysis of nucleotides and aromatic amino acids in normal and neoplastic colon mucosa by ultraviolet resonance raman spectroscopy. Lab Invest 79:1201-14
Zonios, G; Cothren, R; Crawford, J M et al. (1998) Spectral pathology. Ann N Y Acad Sci 838:108-15
Cothren, R M; Sivak Jr, M V; Van Dam, J et al. (1996) Detection of dysplasia at colonoscopy using laser-induced fluorescence: a blinded study. Gastrointest Endosc 44:168-76

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