Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA053765-11
Application #
6512700
Study Section
Special Emphasis Panel (ZRG1-SSS-G (02))
Program Officer
Pelroy, Richard
Project Start
1990-12-04
Project End
2005-03-31
Budget Start
2002-04-01
Budget End
2003-03-31
Support Year
11
Fiscal Year
2002
Total Cost
$464,521
Indirect Cost
Name
George Washington University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
City
Washington
State
DC
Country
United States
Zip Code
20052
Wolnicka-Glubisz, Agnieszka; De Fabo, Edward; Noonan, Frances (2013) Functional melanocortin 1 receptor Mc1r is not necessary for an inflammatory response to UV radiation in adult mouse skin. Exp Dermatol 22:226-8
Noonan, Frances P; Zaidi, M Raza; Wolnicka-Glubisz, Agnieszka et al. (2012) Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment. Nat Commun 3:884
Zaidi, M Raza; Davis, Sean; Noonan, Frances P et al. (2011) Interferon-? links ultraviolet radiation to melanomagenesis in mice. Nature 469:548-53
Wolnicka-Glubisz, Agnieszka; Damsker, Jesse; Constant, Stephanie et al. (2007) Deficient inflammatory response to UV radiation in neonatal mice. J Leukoc Biol 81:1352-61
Wolnicka-Glubisz, Agnieszka; Noonan, Frances P (2006) Neonatal susceptibility to UV induced cutaneous malignant melanoma in a mouse model. Photochem Photobiol Sci 5:254-60
De Fabo, Edward C; Noonan, Frances P; Fears, Thomas et al. (2004) Ultraviolet B but not ultraviolet A radiation initiates melanoma. Cancer Res 64:6372-6
Noonan, Frances P; Muller, H Konrad; Fears, Thomas R et al. (2003) Mice with genetically determined high susceptibility to ultraviolet (UV)-induced immunosuppression show enhanced UV carcinogenesis. J Invest Dermatol 121:1175-81
Clemens, K E; Churchill, G; Bhatt, N et al. (2000) Genetic control of susceptibility to UV-induced immunosuppression by interacting quantitative trait loci. Genes Immun 1:251-9
Hart, P H; Grimbaldeston, M A; Hosszu, E K et al. (1999) Age-related changes in dermal mast cell prevalence in BALB/c mice: functional importance and correlation with dermal mast cell expression of Kit. Immunology 98:352-6
Bouscarel, B; Noonan, F; Ceryak, S et al. (1998) Regulation of stimulated cyclic AMP synthesis by urocanic acid. Photochem Photobiol 67:324-31

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