Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA054560-06
Application #
2096039
Study Section
Pathology B Study Section (PTHB)
Project Start
1991-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Wieland, Stefan F (2015) The chimpanzee model for hepatitis B virus infection. Cold Spring Harb Perspect Med 5:
Chisari, F V; Isogawa, M; Wieland, S F (2010) Pathogenesis of hepatitis B virus infection. Pathol Biol (Paris) 58:258-66
Guidotti, Luca G; Chisari, Francis V (2006) Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol 1:23-61
Schirmbeck, R; Zheng, X; Roggendorf, M et al. (2001) Targeting murine immune responses to selected T cell- or antibody-defined determinants of the hepatitis B surface antigen by plasmid DNA vaccines encoding chimeric antigen. J Immunol 166:1405-13
Schirmbeck, R; Wild, J; Stober, D et al. (2000) Ongoing murine T1 or T2 immune responses to the hepatitis B surface antigen are excluded from the liver that expresses transgene-encoded hepatitis B surface antigen. J Immunol 164:4235-43
Chisari, F V (2000) Rous-Whipple Award Lecture. Viruses, immunity, and cancer: lessons from hepatitis B. Am J Pathol 156:1117-32
Cerny, A; Chisari, F V (1999) Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence. Hepatology 30:595-601
Chisari, F V (1997) Cytotoxic T cells and viral hepatitis. J Clin Invest 99:1472-7
Chisari, F V (1996) Hepatitis B virus transgenic mice: models of viral immunobiology and pathogenesis. Curr Top Microbiol Immunol 206:149-73
Chemin, I; Takahashi, S; Belloc, C et al. (1996) Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis. Hepatology 24:649-56

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