Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA055035-03S1
Application #
2096274
Study Section
Experimental Virology Study Section (EVR)
Project Start
1993-12-15
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Colorado State University-Fort Collins
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
112617480
City
Fort Collins
State
CO
Country
United States
Zip Code
80523
Hansen, Jeffrey C; Nyborg, Jennifer K; Luger, Karolin et al. (2010) Histone chaperones, histone acetylation, and the fluidity of the chromogenome. J Cell Physiol 224:289-99
Luebben, Whitney R; Sharma, Neelam; Nyborg, Jennifer K (2010) Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14. Proc Natl Acad Sci U S A 107:19254-9
Szerlong, Heather J; Prenni, Jessica E; Nyborg, Jennifer K et al. (2010) Activator-dependent p300 acetylation of chromatin in vitro: enhancement of transcription by disruption of repressive nucleosome-nucleosome interactions. J Biol Chem 285:31954-64
Kim, Y-M; Geiger, T R; Egan, D I et al. (2010) The HTLV-1 tax protein cooperates with phosphorylated CREB, TORC2 and p300 to activate CRE-dependent cyclin D1 transcription. Oncogene 29:2142-52
Nyborg, Jennifer K; Egan, Dinaida; Sharma, Neelam (2010) The HTLV-1 Tax protein: revealing mechanisms of transcriptional activation through histone acetylation and nucleosome disassembly. Biochim Biophys Acta 1799:266-74
Ramirez, Julita A; Nyborg, Jennifer K (2007) Molecular characterization of HTLV-1 Tax interaction with the KIX domain of CBP/p300. J Mol Biol 372:958-69
Livengood, Jill A; Nyborg, Jennifer K (2004) The high-affinity Sp1 binding site in the HTLV-1 promoter contributes to Tax-independent basal expression. Nucleic Acids Res 32:2829-37
Livengood, Jill A; Fechter, Eric J; Dervan, Peter B et al. (2004) Paradoxical effects of DNA binding polyamides on HTLV-1 transcription. Front Biosci 9:3058-67
Uittenbogaard, M N; Giebler, H A; Reisman, D et al. (1995) Transcriptional repression of p53 by human T-cell leukemia virus type I Tax protein. J Biol Chem 270:28503-6
Uittenbogaard, M N; Armstrong, A P; Chiaramello, A et al. (1994) Human T-cell leukemia virus type I Tax protein represses gene expression through the basic helix-loop-helix family of transcription factors. J Biol Chem 269:22466-9