Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA055652-06
Application #
2096771
Study Section
Experimental Virology Study Section (EVR)
Project Start
1992-07-16
Project End
2001-06-30
Budget Start
1996-08-21
Budget End
1997-06-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of South Florida
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612
Scuto, A; Kirschbaum, M; Buettner, R et al. (2013) SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-?B/STAT3 complex to its promoter in malignant lymphoid cells. Cell Death Dis 4:e635
Ma, Yuelong; Kowolik, Claudia M; Swiderski, Piotr M et al. (2011) Humanized Lewis-Y specific antibody based delivery of STAT3 siRNA. ACS Chem Biol 6:962-70
Scuto, A; Krejci, P; Popplewell, L et al. (2011) The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival. Leukemia 25:538-50
Scuto, Anna; Kujawski, Maciej; Kowolik, Claudia et al. (2011) STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma. Cancer Res 71:3182-8
Buettner, Ralf; Mesa, Tania; Vultur, Adina et al. (2008) Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells. Mol Cancer Res 6:1766-74
Vultur, Adina; Buettner, Ralf; Kowolik, Claudia et al. (2008) SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. Mol Cancer Ther 7:1185-94
Scuto, Anna; Kirschbaum, Mark; Kowolik, Claudia et al. (2008) The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Blood 111:5093-100
Shor, Audrey C; Keschman, Elizabeth A; Lee, Francis Y et al. (2007) Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival. Cancer Res 67:2800-8
Scuto, Anna; Zhang, Hongling; Zhao, Haiyan et al. (2007) RbAp48 regulates cytoskeletal organization and morphology by increasing K-Ras activity and signaling through mitogen-activated protein kinase. Cancer Res 67:10317-24
Buettner, Ralf; Huang, Mei; Gritsko, Tanya et al. (2007) Activated signal transducers and activators of transcription 3 signaling induces CD46 expression and protects human cancer cells from complement-dependent cytotoxicity. Mol Cancer Res 5:823-32

Showing the most recent 10 out of 69 publications