Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA055852-05
Application #
2096956
Study Section
Pathology B Study Section (PTHB)
Project Start
1992-03-15
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
State University New York Stony Brook
Department
Pathology
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794

  Publications

Deryugina, Elena I; Quigley, James P (2015) Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature. Matrix Biol 44-46:94-112
Deryugina, Elena I; Quigley, James P (2010) Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions. Biochim Biophys Acta 1803:103-20
Ardi, Veronica C; Van den Steen, Philippe E; Opdenakker, Ghislain et al. (2009) Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway. J Biol Chem 284:25854-66
Conn, Erin M; Botkjaer, Kenneth A; Kupriyanova, Tatyana A et al. (2009) Comparative analysis of metastasis variants derived from human prostate carcinoma cells: roles in intravasation of VEGF-mediated angiogenesis and uPA-mediated invasion. Am J Pathol 175:1638-52
Blouse, Grant E; Botkjaer, Kenneth A; Deryugina, Elena et al. (2009) A novel mode of intervention with serine protease activity: targeting zymogen activation. J Biol Chem 284:4647-57
Wortmann, Andreas; He, Yaowu; Deryugina, Elena I et al. (2009) The cell surface glycoprotein CDCP1 in cancer--insights, opportunities, and challenges. IUBMB Life 61:723-30
Conn, Erin M; Madsen, Mark A; Cravatt, Benjamin F et al. (2008) Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation. J Biol Chem 283:26518-27
Deryugina, Elena I; Quigley, James P (2008) Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis. Histochem Cell Biol 130:1119-30
Deryugina, Elena I; Quigley, James P (2008) Chapter 2. Chick embryo chorioallantoic membrane models to quantify angiogenesis induced by inflammatory and tumor cells or purified effector molecules. Methods Enzymol 444:21-41
Partridge, Juneth J; Madsen, Mark A; Ardi, Veronica C et al. (2007) Functional analysis of matrix metalloproteinases and tissue inhibitors of metalloproteinases differentially expressed by variants of human HT-1080 fibrosarcoma exhibiting high and low levels of intravasation and metastasis. J Biol Chem 282:35964-77

Showing the most recent 10 out of 30 publications