Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA056304-03
Application #
2097240
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1994-01-13
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Type
Schools of Arts and Sciences
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Lee, Jihoon; Panek, James S (2011) Total synthesis of (+)-isatisine A. Org Lett 13:502-5
Brawn, Ryan A; Welzel, Morgan; Lowe, Jason T et al. (2010) Regioselective intramolecular dipolar cycloaddition of azides and unsymmetrical alkynes. Org Lett 12:336-9
Wrona, Iwona E; Gozman, Alexander; Taldone, Tony et al. (2010) Synthesis of reblastatin, autolytimycin, and non-benzoquinone analogues: potent inhibitors of heat shock protein 90. J Org Chem 75:2820-35
Brawn, Ryan A; Panek, James S (2009) Annulations of enantioenriched allenylsilanes with in situ generated iminium ions: stereoselective synthesis of diverse heterocycles. Org Lett 11:473-6
Wrona, Iwona E; Lowe, Jason T; Turbyville, Thomas J et al. (2009) Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth. J Org Chem 74:1897-916
Lowe, Jason T; Panek, James S (2008) Total synthesis of (-)-kendomycin. Org Lett 10:3813-6
Qin, Hua-Li; Panek, James S (2008) Total synthesis of the Hsp90 inhibitor geldanamycin. Org Lett 10:2477-9
Qin, Hua-Li; Lowe, Jason T; Panek, James S (2007) Mild reductive opening of aryl pyranosides promoted by scandium(III) triflate. J Am Chem Soc 129:38-9
Lowe, Jason T; Wrona, Iwona E; Panek, James S (2007) Total synthesis of bistramide A. Org Lett 9:327-30
Lowe, Jason T; Youngsaye, Willmen; Panek, James S (2006) A convenient multigram synthesis of highly enantioenriched methyl 3-silylglycidates. J Org Chem 71:3639-42

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