Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
7R01CA058110-03
Application #
3202402
Study Section
Special Emphasis Panel (SRC (70))
Project Start
1992-09-30
Project End
1997-09-29
Budget Start
1994-09-16
Budget End
1994-09-29
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Fang, Peng; Hwa, Vivian; Little, Brian M et al. (2008) IGFBP-3 sensitizes prostate cancer cells to interferon-gamma-induced apoptosis. Growth Horm IGF Res 18:38-46
Hwa, Vivian; Haeusler, Gabriele; Pratt, Katherine L et al. (2006) Total absence of functional acid labile subunit, resulting in severe insulin-like growth factor deficiency and moderate growth failure. J Clin Endocrinol Metab 91:1826-31
Fang, Peng; Kofoed, Eric M; Little, Brian M et al. (2006) A mutant signal transducer and activator of transcription 5b, associated with growth hormone insensitivity and insulin-like growth factor-I deficiency, cannot function as a signal transducer or transcription factor. J Clin Endocrinol Metab 91:1526-34
Fang, Peng; Hwa, Vivian; Rosenfeld, Ron G (2006) Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway. Exp Cell Res 312:1229-39
Hwa, Vivian; Little, Brian; Adiyaman, Pelin et al. (2005) Severe growth hormone insensitivity resulting from total absence of signal transducer and activator of transcription 5b. J Clin Endocrinol Metab 90:4260-6
Rosenfeld, Ron G; Hwa, Vivian (2004) Toward a molecular basis for idiopathic short stature. J Clin Endocrinol Metab 89:1066-7
Hwa, Vivian; Little, Brian; Kofoed, Eric M et al. (2004) Transcriptional regulation of insulin-like growth factor-I by interferon-gamma requires STAT-5b. J Biol Chem 279:2728-36
Kofoed, Eric M; Hwa, Vivian; Little, Brian et al. (2003) Growth hormone insensitivity associated with a STAT5b mutation. N Engl J Med 349:1139-47
Lopez-Bermejo, Abel; Khosravi, Javad; Corless, Christopher L et al. (2003) Generation of anti-insulin-like growth factor-binding protein-related protein 1 (IGFBP-rP1/MAC25) monoclonal antibodies and immunoassay: quantification of IGFBP-rP1 in human serum and distribution in human fluids and tissues. J Clin Endocrinol Metab 88:3401-8
Selva, Karin A; Buckway, Caroline K; Sexton, Gary et al. (2003) Reproducibility in patterns of IGF generation with special reference to idiopathic short stature. Horm Res 60:237-46

Showing the most recent 10 out of 61 publications