Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA059936-04
Application #
2100552
Study Section
Pathology B Study Section (PTHB)
Project Start
1993-04-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Rice, Kim L; Hormaeche, Itsaso; Doulatov, Sergei et al. (2009) Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC. Blood 114:5499-511
Licht, Jonathan D (2009) Acute promyelocytic leukemia--weapons of mass differentiation. N Engl J Med 360:928-30
Doulatov, Sergei; Notta, Faiyaz; Rice, Kim L et al. (2009) PLZF is a regulator of homeostatic and cytokine-induced myeloid development. Genes Dev 23:2076-87
Buzzai, Monica; Licht, Jonathan D (2008) New molecular concepts and targets in acute myeloid leukemia. Curr Opin Hematol 15:82-7
Polo, Jose M; Ci, Weimin; Licht, Jonathan D et al. (2008) Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells. Blood 112:644-51
Petrie, K; Guidez, F; Zhu, J et al. (2008) Retinoblastoma protein and the leukemia-associated PLZF transcription factor interact to repress target gene promoters. Oncogene 27:5260-6
Rice, K L; Hormaeche, I; Licht, J D (2007) Epigenetic regulation of normal and malignant hematopoiesis. Oncogene 26:6697-714
Denne, Miriam; Sauter, Marlies; Armbruester, Vivienne et al. (2007) Physical and functional interactions of human endogenous retrovirus proteins Np9 and rec with the promyelocytic leukemia zinc finger protein. J Virol 81:5607-16
Guidez, Fabien; Howell, Louise; Isalan, Mark et al. (2005) Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein. Mol Cell Biol 25:5552-66
Melnick, Ari M; Adelson, Kerin; Licht, Jonathan D (2005) The theoretical basis of transcriptional therapy of cancer: can it be put into practice? J Clin Oncol 23:3957-70

Showing the most recent 10 out of 63 publications