Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060686-04
Application #
2101442
Study Section
Immunobiology Study Section (IMB)
Project Start
1993-07-07
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Leng, Qibin; Ge, Qing; Nguyen, Tam et al. (2007) Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes. Proc Natl Acad Sci U S A 104:5038-43
Ge, Qing; Holler, Phillip D; Mahajan, Vinay S et al. (2006) Development of CD4+ T cells expressing a nominally MHC class I-restricted T cell receptor by two different mechanisms. Proc Natl Acad Sci U S A 103:1822-7
Palliser, Deborah; Guillen, Eduardo; Ju, Mindy et al. (2005) Multiple intracellular routes in the cross-presentation of a soluble protein by murine dendritic cells. J Immunol 174:1879-87
Palliser, Deborah; Huang, Qian; Hacohen, Nir et al. (2004) A role for Toll-like receptor 4 in dendritic cell activation and cytolytic CD8+ T cell differentiation in response to a recombinant heat shock fusion protein. J Immunol 172:2885-93
Ge, Qing; Bai, Ailin; Jones, Brendan et al. (2004) Competition for self-peptide-MHC complexes and cytokines between naive and memory CD8+ T cells expressing the same or different T cell receptors. Proc Natl Acad Sci U S A 101:3041-6
Little, Steven R; Lynn, David M; Ge, Qing et al. (2004) Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proc Natl Acad Sci U S A 101:9534-9
Ge, Qing; Filip, Lily; Bai, Ailin et al. (2004) Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc Natl Acad Sci U S A 101:8676-81
Rudolph, Markus G; Shen, Lucy Q; Lamontagne, Stephen A et al. (2004) A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects. J Immunol 172:2994-3002
Ge, Qing; Eisen, Herman N; Chen, Jianzhu (2004) Use of siRNAs to prevent and treat influenza virus infection. Virus Res 102:37-42
Chen, Jianzhu; Eisen, Herman N; Kranz, David M (2003) A model T-cell receptor system for studying memory T-cell development. Microbes Infect 5:233-40

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