Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA063230-02
Application #
2104963
Study Section
Pathology B Study Section (PTHB)
Project Start
1995-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105
Wasserman, Jonathan D; Zambetti, Gerard P; Malkin, David (2012) Towards an understanding of the role of p53 in adrenocortical carcinogenesis. Mol Cell Endocrinol 351:101-10
Assumpcao, Juliana G; Seidinger, Ana Luiza; Mastellaro, Maria Jose et al. (2008) Association of the germline TP53 R337H mutation with breast cancer in southern Brazil. BMC Cancer 8:357
Rosati, Roberto; Cerrato, Flavia; Doghman, Mabrouka et al. (2008) High frequency of loss of heterozygosity at 11p15 and IGF2 overexpression are not related to clinical outcome in childhood adrenocortical tumors positive for the R337H TP53 mutation. Cancer Genet Cytogenet 186:19-24
Russell-Swetek, A; West, A N; Mintern, J E et al. (2008) Identification of a novel TP53 germline mutation E285V in a rare case of paediatric adrenocortical carcinoma and choroid plexus carcinoma. J Med Genet 45:603-6
Garrison, Sean P; Jeffers, John R; Yang, Chunying et al. (2008) Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis. Mol Cell Biol 28:5391-402
Doghman, Mabrouka; Arhatte, Malika; Thibout, Helene et al. (2007) Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors. J Clin Endocrinol Metab 92:3253-60
Zambetti, Gerard P (2007) The p53 mutation ""gradient effect"" and its clinical implications. J Cell Physiol 213:370-3
Doghman, Mabrouka; Karpova, Tatiana; Rodrigues, Giovanna Assis et al. (2007) Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer. Mol Endocrinol 21:2968-87
West, Alina Nico; Neale, Geoffrey A; Pounds, Stanley et al. (2007) Gene expression profiling of childhood adrenocortical tumors. Cancer Res 67:600-8
Kim, Hyungjin; Rafiuddin-Shah, Mubina; Tu, Ho-Chou et al. (2006) Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat Cell Biol 8:1348-58

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