|
Shi, Wei; Coleman, Robert S; Lowary, Todd L (2009) Synthesis and DNA-binding affinity studies of glycosylated intercalators designed as functional mimics of the anthracycline antibiotics. Org Biomol Chem 7:3709-22
|
|
Coleman, Robert S; Tierney, Mark T; Cortright, Sarah B et al. (2007) Synthesis of functional ""top-half"" partial structures of azinomycin a and B. J Org Chem 72:7726-35
|
|
Coleman, Robert S; Woodward, Robert L; Hayes, Amy M et al. (2007) Dependence of DNA sequence selectivity and cell cytotoxicity on azinomycin A and B epoxyamide stereochemistry. Org Lett 9:1891-4
|
|
Kelly, Gilbert T; Liu, Chaomin; Smith 3rd, Roger et al. (2006) Cellular effects induced by the antitumor agent azinomycin B. Chem Biol 13:485-92
|
|
Alcaro, Stefano; Ortuso, Francesco; Coleman, Robert S (2005) Molecular modeling of DNA cross-linking analogues based on the azinomycin scaffold. J Chem Inf Model 45:602-9
|
|
Alcaro, Stefano; Ortuso, Francesco; Coleman, Robert S (2002) DNA cross-linking by azinomycin B: Monte Carlo simulations in the evaluation of sequence selectivity. J Med Chem 45:861-70
|
|
Coleman, Robert S; Perez, Ronelito J; Burk, Christopher H et al. (2002) Studies on the mechanism of action of azinomycin B: definition of regioselectivity and sequence selectivity of DNA cross-link formation and clarification of the role of the naphthoate. J Am Chem Soc 124:13008-17
|
|
Coleman, Robert S; Burk, Christopher H; Navarro, Antonio et al. (2002) Role of the azinomycin naphthoate and central amide in sequence-dependent DNA alkylation and cytotoxicity of epoxide-bearing substructures. Org Lett 4:3545-8
|
|
Coleman, R S; Garg, R (2001) Stereocontrolled synthesis of the diene and triene macrolactones of oximidines I and II: organometallic coupling versus standard macrolactonization. Org Lett 3:3487-90
|
|
Coleman, R S (2001) Total synthesis of natural product DNA cross-linking agents. Curr Opin Drug Discov Devel 4:435-49
|
Showing the most recent 10 out of 13 publications
