Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA065896-02
Application #
2109078
Study Section
Radiation Study Section (RAD)
Project Start
1995-02-17
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Cardnell, Robert J G; Mikkelsen, Ross B (2011) Nitric oxide synthase inhibition enhances the antitumor effect of radiation in the treatment of squamous carcinoma xenografts. PLoS One 6:e20147
Yakovlev, Vasily A; Barani, Igor J; Rabender, Christopher S et al. (2007) Tyrosine nitration of IkappaBalpha: a novel mechanism for NF-kappaB activation. Biochemistry 46:11671-83
Contessa, Joseph N; Abell, Angela; Mikkelsen, Ross B et al. (2006) Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation. Breast Cancer Res Treat 95:17-27
Barrett, Daniel M; Black, Stephen M; Todor, Horia et al. (2005) Inhibition of protein-tyrosine phosphatases by mild oxidative stresses is dependent on S-nitrosylation. J Biol Chem 280:14453-61
Sturla, Lisa-Marie; Amorino, George; Alexander, Michael S et al. (2005) Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2. J Biol Chem 280:14597-604
Lammering, Guido; Valerie, Kristoffer; Lin, Peck-Sun et al. (2004) Radiation-induced activation of a common variant of EGFR confers enhanced radioresistance. Radiother Oncol 72:267-73
Lammering, Guido; Hewit, Theodore H; Holmes, Mathew et al. (2004) Inhibition of the type III epidermal growth factor receptor variant mutant receptor by dominant-negative EGFR-CD533 enhances malignant glioma cell radiosensitivity. Clin Cancer Res 10:6732-43
Amorino, George P; Mikkelsen, Ross B; Valerie, Kristoffer et al. (2003) Dominant-negative cAMP-responsive element-binding protein inhibits proliferating cell nuclear antigen and DNA repair, leading to increased cellular radiosensitivity. J Biol Chem 278:29394-9
Holmes, Matthew; Rosenberg, Elizabeth; Valerie, Kristoffer (2003) Adenovirus expressing p53. Methods Mol Biol 234:1-16
Schmidt-Ullrich, Rupert K; Contessa, Joseph N; Lammering, Guido et al. (2003) ERBB receptor tyrosine kinases and cellular radiation responses. Oncogene 22:5855-65

Showing the most recent 10 out of 36 publications