Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA066000-03S1
Application #
2642013
Study Section
Experimental Immunology Study Section (EI)
Project Start
1995-09-01
Project End
1998-08-31
Budget Start
1997-09-01
Budget End
1998-08-31
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Burger, J A; Mendoza, R B; Kipps, T J (2001) Plasmids encoding granulocyte-macrophage colony-stimulating factor and CD154 enhance the immune response to genetic vaccines. Vaccine 19:2181-9
Burger, J A; Baird, S M; Powell, H C et al. (2000) Local and systemic effects after adenoviral transfer of the murine granulocyte-macrophage colony-stimulating factor gene into mice. Br J Haematol 108:641-52
Eling, D J; Johnson, P A; Sharma, S et al. (2000) Chronic lymphocytic leukemia B cells are highly sensitive to infection by herpes simplex virus-1 via herpesvirus-entry-mediator A. Gene Ther 7:1210-6
Hu, D; Kipps, T J (1999) Reduction in mitochondrial membrane potential is an early event in Fas-independent CTL-mediated apoptosis. Cell Immunol 195:43-52
Carter, J D; Neel, B G; Lorenz, U (1999) The tyrosine phosphatase SHP-1 influences thymocyte selection by setting TCR signaling thresholds. Int Immunol 11:1999-2014
Wu, Y; Nadler, M J; Brennan, L A et al. (1998) The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1. Curr Biol 8:1009-17
Kato, K; Cantwell, M J; Sharma, S et al. (1998) Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells. J Clin Invest 101:1133-41
Siminovitch, K A; Neel, B G (1998) Regulation of B cell signal transduction by SH2-containing protein-tyrosine phosphatases. Semin Immunol 10:329-47
Mendoza, R B; Cantwell, M J; Kipps, T J (1997) Immunostimulatory effects of a plasmid expressing CD40 ligand (CD154) on gene immunization. J Immunol 159:5777-81
Wu, Y; Kipps, T J (1997) Deoxyribonucleic acid vaccines encoding antigens with rapid proteasome-dependent degradation are highly efficient inducers of cytolytic T lymphocytes. J Immunol 159:6037-43

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