Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA067529-02
Application #
2111249
Study Section
Special Emphasis Panel (SRC (24))
Project Start
1995-05-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Veterinary Sciences
Type
Other Domestic Higher Education
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Esmail, Michael Y; Bacon, Rebecca; Swennes, Alton G et al. (2016) Helicobacter Species Identified in Captive Sooty Mangabeys (Cercocebus atys) with Metastatic Gastric Adenocarcinoma. Helicobacter 21:175-85
Burns, Monika; Muthupalani, Sureshkumar; Ge, Zhongming et al. (2015) Helicobacter pylori Infection Induces Anemia, Depletes Serum Iron Storage, and Alters Local Iron-Related and Adult Brain Gene Expression in Male INS-GAS Mice. PLoS One 10:e0142630
Caron, Tyler J; Scott, Kathleen E; Fox, James G et al. (2015) Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier. World J Gastroenterol 21:11411-27
Ge, Zhongming; Feng, Yan; Woods, Stephanie E et al. (2015) Spatial and temporal colonization dynamics of segmented filamentous bacteria is influenced by gender, age and experimental infection with Helicobacter hepaticus in Swiss Webster mice. Microbes Infect 17:16-22
Shen, Zeli; Feng, Yan; Rickman, Barry et al. (2015) Helicobacter cinaedi induced typhlocolitis in Rag-2-deficient mice. Helicobacter 20:146-55
Lertpiriyapong, Kvin; Whary, Mark T; Muthupalani, Sureshkumar et al. (2014) Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis. Gut 63:54-63
Hartwell, Hadley J; Petrosky, Keiko Y; Fox, James G et al. (2014) Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice. Proc Natl Acad Sci U S A 111:11455-60
Whary, Mark T; Muthupalani, Sureshkumar; Ge, Zhongming et al. (2014) Helminth co-infection in Helicobacter pylori infected INS-GAS mice attenuates gastric premalignant lesions of epithelial dysplasia and glandular atrophy and preserves colonization resistance of the stomach to lower bowel microbiota. Microbes Infect 16:345-55
Nguyen, Deanna D; Muthupalani, Suresh; Goettel, Jeremy A et al. (2013) Colitis and colon cancer in WASP-deficient mice require helicobacter species. Inflamm Bowel Dis 19:2041-50
Lofgren, Jennifer Ls; Esmail, Michael; Mobley, Melissa et al. (2012) Prevalence of murine Helicobacter spp. Infection is reduced by restocking research colonies with Helicobacter-free mice. J Am Assoc Lab Anim Sci 51:436-42

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