Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA067938-02
Application #
2111751
Study Section
Pathology B Study Section (PTHB)
Project Start
1995-07-15
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105
Choi, H-H; Choi, H-K; Jung, S Y et al. (2014) CHK2 kinase promotes pre-mRNA splicing via phosphorylating CDK11(p110). Oncogene 33:108-15
Delehouzé, C; Godl, K; Loaëc, N et al. (2014) CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells. Oncogene 33:5675-87
Teitz, Tal; Inoue, Madoka; Valentine, Marcus B et al. (2013) Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis. Cancer Res 73:4086-97
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Jiang, Manrong; Stanke, Jennifer; Lahti, Jill M (2011) The connections between neural crest development and neuroblastoma. Curr Top Dev Biol 94:77-127
George, Rani E; Lahti, Jill M; Adamson, Peter C et al. (2010) Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study. Pediatr Blood Cancer 55:629-38
Barbero, Simone; Mielgo, Ainhoa; Torres, Vicente et al. (2009) Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Res 69:3755-63
Jiang, Manrong; Zhu, Kejin; Grenet, Jose et al. (2008) Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells. Biochim Biophys Acta 1783:1055-67
Tekautz, Tanya M; Zhu, Kejin; Grenet, Jose et al. (2006) Evaluation of IFN-gamma effects on apoptosis and gene expression in neuroblastoma--preclinical studies. Biochim Biophys Acta 1763:1000-10
Teitz, Tal; Stupack, Dwayne G; Lahti, Jill M (2006) Halting neuroblastoma metastasis by controlling integrin-mediated death. Cell Cycle 5:681-5

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