Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA068008-01A1
Application #
2111840
Study Section
Pathology B Study Section (PTHB)
Project Start
1996-05-07
Project End
2001-02-28
Budget Start
1996-05-07
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brandeis University
Department
Type
Organized Research Units
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Baum, Karina J; Ren, Ruibao (2008) Effect of Ras inhibition in hematopoiesis and BCR/ABL leukemogenesis. J Hematol Oncol 1:5
Acquaviva, Jaime; Chen, Xiaoren; Ren, Ruibao (2008) IRF-4 functions as a tumor suppressor in early B-cell development. Blood 112:3798-806
Parikh, Chaitali; Ren, Ruibao (2008) Mouse model for NRAS-induced leukemogenesis. Methods Enzymol 439:15-24
Parikh, Chaitali; Subrahmanyam, Ramesh; Ren, Ruibao (2006) Oncogenic NRAS rapidly and efficiently induces CMML- and AML-like diseases in mice. Blood 108:2349-57
Ren, Ruibao (2004) Modeling the dosage effect of oncogenes in leukemogenesis. Curr Opin Hematol 11:25-34
Cuenco, Grace M; Ren, Ruibao (2004) Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice. Oncogene 23:569-79
Wertheim, Jason A; Perera, Samanthi A; Hammer, Daniel A et al. (2003) Localization of BCR-ABL to F-actin regulates cell adhesion but does not attenuate CML development. Blood 102:2220-8
Ren, Ruibao (2002) Dissecting the molecular mechanism of chronic myelogenous leukemia using murine models. Leuk Lymphoma 43:1549-61
Ren, Ruibao (2002) The molecular mechanism of chronic myelogenous leukemia and its therapeutic implications: studies in a murine model. Oncogene 21:8629-42
Zhang, X; Subrahmanyam, R; Wong, R et al. (2001) The NH(2)-terminal coiled-coil domain and tyrosine 177 play important roles in induction of a myeloproliferative disease in mice by Bcr-Abl. Mol Cell Biol 21:840-53

Showing the most recent 10 out of 16 publications