Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA069571-01
Application #
2113623
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1996-08-01
Project End
2000-05-31
Budget Start
1996-08-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Polytechnic Institute and State University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
003137015
City
Blacksburg
State
VA
Country
United States
Zip Code
24061
Ganesh, Thota; Brodie, Peggy J; Banerjee, Abhijit et al. (2014) Synthesis of isotopically labeled epothilones. J Labelled Comp Radiopharm 57:78-81
Kingston, David G I; Snyder, James P (2014) The quest for a simple bioactive analog of paclitaxel as a potential anticancer agent. Acc Chem Res 47:2682-91
Sharma, Shubhada; Lagisetti, Chandraiah; Poliks, Barbara et al. (2013) Dissecting paclitaxel-microtubule association: quantitative assessment of the 2'-OH group. Biochemistry 52:2328-36
Kingston, David G I; Tamarkin, Lawrence; Paciotti, Giulio F (2012) Conformationally Constrained and Nanoparticle Targeted Paclitaxels. Pure Appl Chem 84:1455-1467
Zhan, Weiqiang; Jiang, Yi; Sharma, Shubhada et al. (2011) C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle. Chemistry 17:14792-804
Zhao, Jielu; Bane, Susan; Snyder, James P et al. (2011) Design and synthesis of simplified taxol analogs based on the T-Taxol bioactive conformation. Bioorg Med Chem 19:7664-78
Dilek, Ozlem; Bane, Susan L (2011) Synthesis and spectroscopic characterization of fluorescent boron dipyrromethene-derived hydrazones. J Fluoresc 21:347-54
Qi, Jun; Blanden, Adam R; Bane, Susan et al. (2011) Design, synthesis and biological evaluation of a simplified fluorescently labeled discodermolide as a molecular probe to study the binding of discodermolide to tubulin. Bioorg Med Chem 19:5247-54
Shanker, Natasha; Dilek, Ozlem; Mukherjee, Kamalika et al. (2011) Aurones: small molecule visible range fluorescent probes suitable for biomacromolecules. J Fluoresc 21:2173-84
Banerjee, Abhijit; Bovenzi, Frank A; Bane, Susan L (2010) High-resolution separation of tubulin monomers on polyacrylamide minigels. Anal Biochem 402:194-6

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