Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA070196-01
Application #
2114135
Study Section
Pathology B Study Section (PTHB)
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Haffner, Michael C; Esopi, David M; Chaux, Alcides et al. (2017) AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination. Nat Commun 8:142
Munari, Enrico; Chaux, Alcides; Vaghasia, Ajay M et al. (2016) Global 5-Hydroxymethylcytosine Levels Are Profoundly Reduced in Multiple Genitourinary Malignancies. PLoS One 11:e0146302
Haffner, Michael C; Weier, Christopher; Xu, Meng Meng et al. (2016) Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization. J Pathol 238:31-41
Hedayati, Mohammad; Haffner, Michael C; Coulter, Jonathan B et al. (2016) Androgen Deprivation Followed by Acute Androgen Stimulation Selectively Sensitizes AR-Positive Prostate Cancer Cells to Ionizing Radiation. Clin Cancer Res 22:3310-3319
Wyhs, Nicolas; Walker, David; Giovinazzo, Hugh et al. (2014) Time-Resolved Fluorescence Resonance Energy Transfer Assay for Discovery of Small-Molecule Inhibitors of Methyl-CpG Binding Domain Protein 2. J Biomol Screen 19:1060-9
Aryee, Martin J; Liu, Wennuan; Engelmann, Julia C et al. (2013) DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases. Sci Transl Med 5:169ra10
Haffner, Michael C; Mosbruger, Timothy; Esopi, David M et al. (2013) Tracking the clonal origin of lethal prostate cancer. J Clin Invest 123:4918-22
Weier, Christopher; Haffner, Michael C; Mosbruger, Timothy et al. (2013) Nucleotide resolution analysis of TMPRSS2 and ERG rearrangements in prostate cancer. J Pathol 230:174-83
Haffner, Michael C; Pellakuru, Laxmi G; Ghosh, Susmita et al. (2013) Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease. Cell Cycle 12:1835-41
Shinohara, Debika Biswal; Vaghasia, Ajay M; Yu, Shu-Han et al. (2013) A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes. Prostate 73:1007-15

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