Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA070244-01
Application #
2114175
Study Section
Pathology B Study Section (PTHB)
Project Start
1996-06-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Jiang, Tianyun; Collins, Brendan J; Jin, Ning et al. (2009) Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer. Cancer Res 69:845-54
Nakakura, Eric K; Sriuranpong, Virote R; Kunnimalaiyaan, Muthusamy et al. (2005) Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling. J Clin Endocrinol Metab 90:4350-6
Ball, Douglas W (2004) Achaete-scute homolog-1 and Notch in lung neuroendocrine development and cancer. Cancer Lett 204:159-69
Collins, Brendan J; Kleeberger, Wolfram; Ball, Douglas W (2004) Notch in lung development and lung cancer. Semin Cancer Biol 14:357-64
Fan, Xing; Mikolaenko, Irina; Elhassan, Ihab et al. (2004) Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Res 64:7787-93
Esni, Farzad; Ghosh, Bidyut; Biankin, Andrew V et al. (2004) Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas. Development 131:4213-24
Park, Jong-In; Strock, Christopher J; Ball, Douglas W et al. (2003) The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway. Mol Cell Biol 23:543-54
Ball, Douglas W; Leach, Steven D (2003) Notch in malignancy. Cancer Treat Res 115:95-121
Miyamoto, Yoshiharu; Maitra, Anirban; Ghosh, Bidyut et al. (2003) Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 3:565-76
Sriuranpong, Virote; Borges, Michael W; Strock, Christopher L et al. (2002) Notch signaling induces rapid degradation of achaete-scute homolog 1. Mol Cell Biol 22:3129-39

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