Bates, Darcy J P; Smitherman, Pamela K; Townsend, Alan J et al. (2011) Nitroalkene fatty acids mediate activation of Nrf2/ARE-dependent and PPARýý-dependent transcription by distinct signaling pathways and with significantly different potencies. Biochemistry 50:7765-73
|
Rudd, Lisa P; Kabler, Sandra L; Morrow, Charles S et al. (2011) Enhanced glutathione depletion, protein adduct formation, and cytotoxicity following exposure to 4-hydroxy-2-nonenal (HNE) in cells expressing human multidrug resistance protein-1 (MRP1) together with human glutathione S-transferase-M1 (GSTM1). Chem Biol Interact 194:113-9
|
Bates, Darcy J P; Lively, Mark O; Gorczynski, Michael J et al. (2009) Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma. Biochemistry 48:4159-69
|
Alexander, Richard L; Wright, Marcus W; Gorczynski, Michael J et al. (2009) Differential potencies of naturally occurring regioisomers of nitrolinoleic acid in PPARgamma activation. Biochemistry 48:492-8
|
Gorczynski, Michael J; Smitherman, Pamela K; Akiyama, Taro E et al. (2009) Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by nitroalkene fatty acids: importance of nitration position and degree of unsaturation. J Med Chem 52:4631-9
|
Peklak-Scott, Christina; Smitherman, Pamela K; Townsend, Alan J et al. (2008) Role of glutathione S-transferase P1-1 in the cellular detoxification of cisplatin. Mol Cancer Ther 7:3247-55
|
Sibhatu, Mebrahtu B; Smitherman, Pamela K; Townsend, Alan J et al. (2008) Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane. Carcinogenesis 29:807-15
|
Alexander, Richard L; Bates, Darcy J P; Wright, Marcus W et al. (2006) Modulation of nitrated lipid signaling by multidrug resistance protein 1 (MRP1): glutathione conjugation and MRP1-mediated efflux inhibit nitrolinoleic acid-induced, PPARgamma-dependent transcription activation. Biochemistry 45:7889-96
|
Morrow, Charles S; Peklak-Scott, Christina; Bishwokarma, Bimjhana et al. (2006) Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux. Mol Pharmacol 69:1499-505
|
O'Flaherty, Joseph T; Rogers, LeAnn C; Paumi, Christian M et al. (2005) 5-Oxo-ETE analogs and the proliferation of cancer cells. Biochim Biophys Acta 1736:228-36
|
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