Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA073385-02S1
Application #
2646452
Study Section
Special Emphasis Panel (SRC (02))
Project Start
1996-09-30
Project End
2000-07-31
Budget Start
1997-08-01
Budget End
1998-07-31
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Long Island Jewish Medical Center
Department
Type
DUNS #
City
New Hyde Park
State
NY
Country
United States
Zip Code
11040
Qi, Mei; Anderson, Ann E; Chen, Da-Zhi et al. (2005) Indole-3-carbinol prevents PTEN loss in cervical cancer in vivo. Mol Med 11:59-63
Chen, Dazhi; Carter, Timothy H; Auborn, Karen J (2004) Apoptosis in cervical cancer cells: implications for adjunct anti-estrogen therapy for cervical cancer. Anticancer Res 24:2649-56
Auborn, Karen J; Qi, Mei; Yan, Xiao J et al. (2003) Lifespan is prolonged in autoimmune-prone (NZB/NZW) F1 mice fed a diet supplemented with indole-3-carbinol. J Nutr 133:3610-3
Qi, Mei; Chen, DaZhi; Liu, Kai et al. (2002) n-6 Polyunsaturated fatty acids increase skin but not cervical cancer in human papillomavirus 16 transgenic mice. Cancer Res 62:433-6
Chen, D Z; Qi, M; Auborn, K J et al. (2001) Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium. J Nutr 131:3294-302
Auborn, K J; Carter, T H (2000) Treatment of human papillomavirus gynecologic infections. Clin Lab Med 20:407-22
Meng, Q; Yuan, F; Goldberg, I D et al. (2000) Indole-3-carbinol is a negative regulator of estrogen receptor-alpha signaling in human tumor cells. J Nutr 130:2927-31
Yuan, F; Chen, D Z; Liu, K et al. (1999) Anti-estrogenic activities of indole-3-carbinol in cervical cells: implication for prevention of cervical cancer. Anticancer Res 19:1673-80
Chen, D; Auborn, K (1999) Fish oil constituent docosahexa-enoic acid selectively inhibits growth of human papillomavirus immortalized keratinocytes. Carcinogenesis 20:249-54
Jin, L; Qi, M; Chen, D Z et al. (1999) Indole-3-carbinol prevents cervical cancer in human papilloma virus type 16 (HPV16) transgenic mice. Cancer Res 59:3991-7

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