Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA080789-04
Application #
6513484
Study Section
Special Emphasis Panel (ZRG1-MEP (01))
Program Officer
Woodhouse, Elizabeth
Project Start
1999-07-01
Project End
2003-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
4
Fiscal Year
2002
Total Cost
$311,390
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Goel, Hira Lal; Pursell, Bryan; Chang, Cheng et al. (2013) GLI1 regulates a novel neuropilin-2/?6?1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med 5:488-508
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Goel, Hira Lal; Pursell, Bryan; Standley, Clive et al. (2012) Neuropilin-2 regulates ýý6ýý1 integrin in the formation of focal adhesions and signaling. J Cell Sci 125:497-506
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Goel, Hira Lal; Chang, Cheng; Pursell, Bryan et al. (2012) VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer. Cancer Discov 2:906-21
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Yang, Xiaofang; Pursell, Bryan; Lu, Shaolei et al. (2009) Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition. J Cell Sci 122:2473-80
Lu, Shaolei; Simin, Karl; Khan, Ashraf et al. (2008) Analysis of integrin beta4 expression in human breast cancer: association with basal-like tumors and prognostic significance. Clin Cancer Res 14:1050-8
Merdek, Keith D; Yang, Xiaoqing; Taglienti, Cherie A et al. (2007) Intrinsic signaling functions of the beta4 integrin intracellular domain. J Biol Chem 282:30322-30

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