Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA084408-02
Application #
6329107
Study Section
Radiation Study Section (RAD)
Program Officer
Stone, Helen B
Project Start
2000-01-24
Project End
2003-11-30
Budget Start
2000-12-01
Budget End
2001-11-30
Support Year
2
Fiscal Year
2001
Total Cost
$258,236
Indirect Cost
Name
University of Florida
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Biel, Nikolett M; Siemann, Dietmar W (2016) Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference. Cancer Lett 380:525-33
Magdoom, Kulam Najmudeen; Pishko, Gregory L; Rice, Lori et al. (2014) MRI-based computational model of heterogeneous tracer transport following local infusion into a mouse hind limb tumor. PLoS One 9:e89594
Siemann, Dietmar W (2011) The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents. Cancer Treat Rev 37:63-74
Bertelsen, Lotte B; Shen, Yuan Yuan; Nielsen, Thomas et al. (2011) Vascular effects of plinabulin (NPI-2358) and the influence on tumour response when given alone or combined with radiation. Int J Radiat Biol 87:1126-34
Rice, Lori; Pampo, Christine; Lepler, Sharon et al. (2011) Support of a free radical mechanism for enhanced antitumor efficacy of the microtubule disruptor OXi4503. Microvasc Res 81:44-51
Madlambayan, Gerard J; Meacham, Amy M; Hosaka, Koji et al. (2010) Leukemia regression by vascular disruption and antiangiogenic therapy. Blood 116:1539-47
Wankhede, Mamta; Dedeugd, Casey; Siemann, Dietmar W et al. (2010) In vivo functional differences in microvascular response of 4T1 and Caki-1 tumors after treatment with OXi4503. Oncol Rep 23:685-92
Baguley, Bruce C; Siemann, Dietmar W (2010) Temporal aspects of the action of ASA404 (vadimezan; DMXAA). Expert Opin Investig Drugs 19:1413-25
Siemann, Dietmar W; Horsman, Michael R (2009) Vascular targeted therapies in oncology. Cell Tissue Res 335:241-8
Siemann, Dietmar W; Chaplin, David J; Walicke, Patricia A (2009) A review and update of the current status of the vasculature-disabling agent combretastatin-A4 phosphate (CA4P). Expert Opin Investig Drugs 18:189-97

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