Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA085344-04
Application #
6514394
Study Section
Chemical Pathology Study Section (CPA)
Program Officer
Okano, Paul
Project Start
1999-07-01
Project End
2003-06-30
Budget Start
2002-05-01
Budget End
2003-06-30
Support Year
4
Fiscal Year
2002
Total Cost
$190,137
Indirect Cost
Name
City of Hope/Beckman Research Institute
Department
Type
DUNS #
City
Duarte
State
CA
Country
United States
Zip Code
91010
Li, Zhengke; Liu, Bochao; Jin, Weiwei et al. (2018) hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability. EMBO J 37:
Xu, Xiaoliang L; Li, Zhengke; Liu, Aihong et al. (2017) SKP2 Activation by Thyroid Hormone Receptor ?2 Bypasses Rb-Dependent Proliferation in Rb-Deficient Cells. Cancer Res 77:6838-6850
Sun, H; He, L; Wu, H et al. (2017) The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation. Oncogene 36:194-207
Zheng, Li; Jia, Jia; Dai, Huifang et al. (2017) Triptolide-Assisted Phosphorylation of p53 Suppresses Inflammation-Induced NF-?B Survival Pathways in Cancer Cells. Mol Cell Biol 37:
Chu, Fong-Fong; Esworthy, R Steven; Doroshow, James H et al. (2017) Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium. Redox Biol 11:144-156
Zhang, Shirong; Wu, Kan; Feng, Jianguo et al. (2016) Epigenetic therapy potential of suberoylanilide hydroxamic acid on invasive human non-small cell lung cancer cells. Oncotarget 7:68768-68780
Chu, Fong-Fong; Esworthy, R Steven; Doroshow, James H et al. (2016) NADPH oxidase-1 deficiency offers little protection in Salmonella typhimurium-induced typhlitis in mice. World J Gastroenterol 22:10158-10165
Pan, Xiao; Cang, Xiaohui; Dan, Songsong et al. (2016) Site-specific Disruption of the Oct4/Sox2 Protein Interaction Reveals Coordinated Mesendodermal Differentiation and the Epithelial-Mesenchymal Transition. J Biol Chem 291:18353-69
Liu, Wenpeng; Zhou, Mian; Li, Zhengke et al. (2016) A Selective Small Molecule DNA2 Inhibitor for Sensitization of Human Cancer Cells to Chemotherapy. EBioMedicine 6:73-86
Zhou, Ting; Pan, Feiyan; Cao, Yan et al. (2016) R152C DNA Pol ? mutation impairs base excision repair and induces cellular transformation. Oncotarget 7:6902-15

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