Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA093678-02
Application #
6694028
Study Section
Experimental Immunology Study Section (EI)
Program Officer
Howcroft, Thomas K
Project Start
2002-12-31
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$268,137
Indirect Cost
Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Thompson, Thornton W; Jackson, Benjamin T; Li, P Jonathan et al. (2018) Tumor-derived CSF-1 induces the NKG2D ligand RAE-1? on tumor-infiltrating macrophages. Elife 7:
Hsu, Joy; Hodgins, Jonathan J; Marathe, Malvika et al. (2018) Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade. J Clin Invest 128:4654-4668
Kerdiles, Yann M; Almeida, Francisca F; Thompson, Thornton et al. (2017) Natural-Killer-like B Cells Display the Phenotypic and Functional Characteristics of Conventional B Cells. Immunity 47:199-200
Campbell, Amanda R; Duggan, Megan C; Suarez-Kelly, Lorena P et al. (2017) MICA-Expressing Monocytes Enhance Natural Killer Cell Fc Receptor-Mediated Antitumor Functions. Cancer Immunol Res 5:778-789
Vance, Russell E; Eichberg, Michael J; Portnoy, Daniel A et al. (2017) Listening to each other: Infectious disease and cancer immunology. Sci Immunol 2:
Thompson, Thornton W; Kim, Alexander Byungsuk; Li, P Jonathan et al. (2017) Endothelial cells express NKG2D ligands and desensitize antitumor NK responses. Elife 6:
Raulet, David H; Marcus, Assaf; Coscoy, Laurent (2017) Dysregulated cellular functions and cell stress pathways provide critical cues for activating and targeting natural killer cells to transformed and infected cells. Immunol Rev 280:93-101
Spiegel, Asaf; Brooks, Mary W; Houshyar, Samin et al. (2016) Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells. Cancer Discov 6:630-49
Iannello, Alexandre; Thompson, Thornton W; Ardolino, Michele et al. (2016) Immunosurveillance and immunotherapy of tumors by innate immune cells. Curr Opin Immunol 38:52-8
Deng, Weiwen; Gowen, Benjamin G; Zhang, Li et al. (2015) Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection. Science 348:136-9

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