Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
2R01DA003590-12A1
Application #
6039801
Study Section
Special Emphasis Panel (ZRG1-MDCN-5 (01))
Program Officer
Hillery, Paul
Project Start
1984-07-01
Project End
2004-12-31
Budget Start
2000-01-01
Budget End
2000-12-31
Support Year
12
Fiscal Year
2000
Total Cost
$156,851
Indirect Cost
Name
Clemson University
Department
Chemistry
Type
Schools of Engineering
DUNS #
042629816
City
Clemson
State
SC
Country
United States
Zip Code
29634
Breivogel, Christopher S; Puri, Vanita; Lambert, Jonathan M et al. (2013) The influence of beta-arrestin2 on cannabinoid CB1 receptor coupling to G-proteins and subcellular localization and relative levels of beta-arrestin1 and 2 in mouse brain. J Recept Signal Transduct Res 33:367-79
Wiley, Jenny L; Marusich, Julie A; Martin, Billy R et al. (2012) 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice. Drug Alcohol Depend 123:148-53
Wiley, Jenny L; Breivogel, Christopher S; Mahadevan, Anu et al. (2011) Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist. Eur J Pharmacol 651:96-105
Huffman, John W; Hepburn, Seon A; Reggio, Patricia H et al. (2010) Synthesis and pharmacology of 1-methoxy analogs of CP-47,497. Bioorg Med Chem 18:5475-82
Chen, Jianhong; Smith, Valerie J; Huffman, John W (2010) 8-Chloro- and 5,8-Dichloro1-naphthoic Acids. Org Prep Proced Int 42:490-493
Huffman, John W; Hepburn, Seon A; Lyutenko, Nataliya et al. (2010) 1-Bromo-3-(1',1'-dimethylalkyl)-1-deoxy-?(8)-tetrahydrocannabinols: New selective ligands for the cannabinoid CB(2) receptor. Bioorg Med Chem 18:7809-15
Atwood, Brady K; Huffman, John; Straiker, Alex et al. (2010) JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist. Br J Pharmacol 160:585-93
Vann, Robert E; Warner, Jonathan A; Bushell, Kristen et al. (2009) Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. Eur J Pharmacol 615:102-7
Huffman, John W; Thompson, Alicia L S; Wiley, Jenny L et al. (2008) Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg Med Chem 16:322-35
Poso, A; Huffman, J W (2008) Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands. Br J Pharmacol 153:335-46

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