Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA004315-11S1
Application #
2631525
Study Section
Special Emphasis Panel (SRCD (04))
Project Start
1986-09-30
Project End
2000-06-30
Budget Start
1997-07-01
Budget End
1998-06-30
Support Year
11
Fiscal Year
1997
Total Cost
Indirect Cost
Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Wang, Jianhui; Zhang, Wei; Yi, Zanhua et al. (2012) Identification of a thrombin cleavage site and a short form of ADAMTS-18. Biochem Biophys Res Commun 419:692-7
Pan, Ruimin; Wang, Jianhui; Nardi, Michael A et al. (2011) The inhibition effect of anti-GPIIIa49-66 antibody on megakaryocyte differentiation. Thromb Haemost 106:484-90
Wang, Jianhui; Yi, Zanhua; Wang, Shiyang et al. (2011) The effect of decitabine on megakaryocyte maturation and platelet release. Thromb Haemost 106:337-43
Dang, Suying; Hong, Tao; Wisniewski, Thomas et al. (2011) Dissolution of pre-existing platelet thrombus by synergistic administration of low concentrations of bifunctional antibodies against ?3 integrin. PLoS One 6:e27012
Wang, J; Zhang, W; Nardi, M A et al. (2011) HIV-1 Tat-induced platelet activation and release of CD154 contribute to HIV-1-associated autoimmune thrombocytopenia. J Thromb Haemost 9:562-73
Zhang, Wei; Li, Yong-Sheng; Nardi, Michael A et al. (2010) Dissolution of arterial platelet thrombi in vivo with a bifunctional platelet GPIIIa49-66 ligand which specifically targets the platelet thrombus. Blood 116:2336-44
Zhang, Wei; Dang, Suying; Wang, Jianhui et al. (2010) Specific cross-reaction of anti-dsDNA antibody with platelet integrin GPIIIa49-66. Autoimmunity 43:682-9
Li, Zongdong; Nardi, Michael A; Li, Yong-Sheng et al. (2009) C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke. Blood 113:6051-60
Hu, Liang; Ibrahim, Sherif; Liu, Cynthia et al. (2009) Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222. Cancer Res 69:3374-81
Nardi, Michael A; Gor, Yelena; Feinmark, Steven J et al. (2007) Platelet particle formation by anti GPIIIa49-66 Ab, Ca2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A2, 12-lipoxygenase, and NADPH oxidase. Blood 110:1989-96

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