Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA004381-10
Application #
2117165
Study Section
Sociobehavioral Subcommittee (DAAR)
Project Start
1987-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Minneapolis Medical Research Fdn, Inc.
Department
Type
DUNS #
City
Minneapolis
State
MN
Country
United States
Zip Code
55415
El Ghazi, Issam; Sheng, Wen S; Hu, Shuxian et al. (2010) Changes in the NMR metabolic profile of human microglial cells exposed to lipopolysaccharide or morphine. J Neuroimmune Pharmacol 5:574-81
Rock, R Bryan; Gekker, Genya; Hu, Shuxian et al. (2007) WIN55,212-2-mediated inhibition of HIV-1 expression in microglial cells: involvement of cannabinoid receptors. J Neuroimmune Pharmacol 2:178-83
Shideman, C R; Hu, S; Peterson, P K et al. (2006) CCL5 evokes calcium signals in microglia through a kinase-, phosphoinositide-, and nucleotide-dependent mechanism. J Neurosci Res 83:1471-84
Rock, R Bryan; Peterson, Phillip K (2006) Microglia as a pharmacological target in infectious and inflammatory diseases of the brain. J Neuroimmune Pharmacol 1:117-26
Clark 3rd, J P; Sampair, Christopher S; Kofuji, Paulo et al. (2005) HIV protein, transactivator of transcription, alters circadian rhythms through the light entrainment pathway. Am J Physiol Regul Integr Comp Physiol 289:R656-62
Rock, R Bryan; Hu, Shuxian; Gekker, Genya et al. (2005) Mycobacterium tuberculosis-induced cytokine and chemokine expression by human microglia and astrocytes: effects of dexamethasone. J Infect Dis 192:2054-8
Rock, R B; Hu, S; Deshpande, A et al. (2005) Transcriptional response of human microglial cells to interferon-gamma. Genes Immun 6:712-9
Hu, Shuxian; Sheng, Wen S; Lokensgard, James R et al. (2005) Morphine potentiates HIV-1 gp120-induced neuronal apoptosis. J Infect Dis 191:886-9
Peterson, P K; Gekker, G; Hu, S et al. (2004) Cannabinoids and morphine differentially affect HIV-1 expression in CD4(+) lymphocyte and microglial cell cultures. J Neuroimmunol 147:123-6
Rock, R Bryan; Gekker, Genya; Hu, Shuxian et al. (2004) Role of microglia in central nervous system infections. Clin Microbiol Rev 17:942-64, table of contents

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