Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA005161-07
Application #
2117481
Study Section
Special Emphasis Panel (SRCD (02))
Project Start
1989-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
North Shore University Hospital
Department
Type
DUNS #
City
Manhasset
State
NY
Country
United States
Zip Code
11030
McCloskey, Thomas W; Haridas, Viraga; Pontrelli, Lucy et al. (2004) Response to superantigen stimulation in peripheral blood mononuclear cells from children perinatally infected with human immunodeficiency virus and receiving highly active antiretroviral therapy. Clin Diagn Lab Immunol 11:957-62
McCloskey, T W; Chavan, S; Lakshmi Tamma, S M et al. (1998) Comparison of seven quantitative assays to assess lymphocyte cell death during HIV infection: measurement of induced apoptosis in anti-Fas-treated Jurkat cells and spontaneous apoptosis in peripheral blood mononuclear cells from children infected with HIV AIDS Res Hum Retroviruses 14:1413-22
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Hu, R; Oyaizu, N; Kalyanaraman, V S et al. (1994) HIV-1 gp160 as a modifier of Th1 and Th2 cytokine response: gp160 suppresses interferon-gamma and interleukin-2 production concomitantly with enhanced interleukin-4 production in vitro. Clin Immunol Immunopathol 73:245-51
Gurram, M; Chirmule, N; Wang, X P et al. (1994) Increased spontaneous secretion of interleukin 6 and tumor necrosis factor alpha by peripheral blood lymphocytes of human immunodeficiency virus-infected children. Pediatr Infect Dis J 13:496-501
Chirmule, N; Wang, X P; Hu, R et al. (1994) Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help. Cell Immunol 155:169-82
McCloskey, T W; Oyaizu, N; Coronesi, M et al. (1994) Use of a flow cytometric assay to quantitate apoptosis in human lymphocytes. Clin Immunol Immunopathol 71:14-8
Chirmule, N; Kalyanaraman, V S; Pahwa, S (1994) Signals transduced through the CD4 molecule on T lymphocytes activate NF-kappa B. Biochem Biophys Res Commun 203:498-505
Chirmule, N; Kalyanaraman, V S; Lederman, S et al. (1993) HIV-gp 160-induced T cell-dependent B cell differentiation. Role of T cell-B cell activation molecule and IL-6. J Immunol 150:2478-86

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