Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA005181-13
Application #
6489462
Study Section
Special Emphasis Panel (ZRG1-MDCN-5 (01))
Program Officer
Lin, Geraline
Project Start
1988-03-01
Project End
2003-12-31
Budget Start
2002-01-01
Budget End
2002-12-31
Support Year
13
Fiscal Year
2002
Total Cost
$258,512
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Pharmacology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Canal, Clinton E; Olaghere da Silva, Uade B; Gresch, Paul J et al. (2010) The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen. Psychopharmacology (Berl) 209:163-74
Benneyworth, Michael A; Smith, Randy L; Sanders-Bush, Elaine (2008) Chronic phenethylamine hallucinogen treatment alters behavioral sensitivity to a metabotropic glutamate 2/3 receptor agonist. Neuropsychopharmacology 33:2206-16
Garcia, Efrain E; Smith, Randy L; Sanders-Bush, Elaine (2007) Role of G(q) protein in behavioral effects of the hallucinogenic drug 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane. Neuropharmacology 52:1671-7
Gresch, P J; Strickland, L V; Sanders-Bush, E (2002) Lysergic acid diethylamide-induced Fos expression in rat brain: role of serotonin-2A receptors. Neuroscience 114:707-13
Grotewiel, M S; Chu, H; Sanders-Bush, E (1994) m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine are partial agonists at cloned 5-HT2A receptors expressed in fibroblasts. J Pharmacol Exp Ther 271:1122-6
Barker, E L; Sanders-Bush, E (1993) 5-hydroxytryptamine1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Mol Pharmacol 44:725-30
Burris, K D; Sanders-Bush, E (1992) Unsurmountable antagonism of brain 5-hydroxytryptamine2 receptors by (+)-lysergic acid diethylamide and bromo-lysergic acid diethylamide. Mol Pharmacol 42:826-30
Barker, E L; Burris, K D; Sanders-Bush, E (1991) Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus. Brain Res 552:330-2
Sanders-Bush, E; Breeding, M (1991) Choroid plexus epithelial cells in primary culture: a model of 5HT1C receptor activation by hallucinogenic drugs. Psychopharmacology (Berl) 105:340-6
Esterle, T M; Sanders-Bush, E (1991) From neurotransmitter to gene: identifying the missing links. Trends Pharmacol Sci 12:375-9

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