This competing continuation application is to fund the next wave of a long-term ongoing, longitudinal study. This longitudinal study examines the etiologic determinants of changes between adolescence and adulthood in drug use and other problem behaviors, and the consequences of drug use and abuse/dependence on the individual's functioning. The sample includes disadvantaged inner city African American and Puerto Rican adults who were seen in early/middle adolescence, and then in late adolescence. A fourth data collection is proposed to accomplish the following: (1) To examine the interrelations and interactions of risk and protective factors, including personality, family, peers, ecological context, acculturation/cultural values, and African American and Puerto Rican ethnic identification, as they affect the course of drug use (i.e., onset, stability, cessation) and abuse/dependence, delinquency, and risky sexual activity in these adults; and (2) To study the consequences of early drug use and abuse/dependence and other problem behaviors on adult intraand interpersonal functioning. Telephone interviews with the adult subjects will be conducted by trained ethnically matched interviewers. Scales with adequate psychometric properties measuring the independent variables will be developed from the interview schedules. The primary analytic techniques will be LISREL, hierarchical regression analysis, and logistic regression analysis. The significance of this study lies in its longitudinal design with intrapersonal, interpersonal, and problem behavior data available in depth on adult, inner city African Americans and Puerto Ricans. This is the first time such longitudinal data will be available for so large a sample in this age group at particular risk for increased drug use and abuse/dependence. Knowledge of the protective factors which help offset the risks for drug use and abuse/dependence, and knowledge of the consequences of such use for psychosocial functioning are important for determining the foci and timing of effective prevention and treatment programs.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
2R01DA005702-14
Application #
6598253
Study Section
Special Emphasis Panel (ZRG1-SNEM-1 (01))
Program Officer
Chambers, Jessica Campbell
Project Start
1993-06-01
Project End
2004-01-31
Budget Start
2003-05-01
Budget End
2004-01-31
Support Year
14
Fiscal Year
2003
Total Cost
$471,729
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2018) Trajectories of cannabis use beginning in adolescence associated with symptoms of posttraumatic stress disorder in the mid-thirties. Subst Abus 39:39-45
Lee, Jung Yeon; Brook, Judith S; De La Rosa, Mario et al. (2017) The association between alcohol use trajectories from adolescence to adulthood and cannabis use disorder in adulthood: a 22-year longitudinal study. Am J Drug Alcohol Abuse 43:727-733
Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2017) Joint trajectories of cigarette smoking and depressive symptoms from the mid-20s to the mid-30s predicting generalized anxiety disorder. J Addict Dis 36:158-166
Lee, Jung Yeon; Brook, Judith S; Pahl, Kerstin et al. (2017) Longitudinal pathways from unconventional personal attributes in the late 20s to cannabis use prior to sexual intercourse in the late 30s. Addict Behav 74:148-152
Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2016) An Adverse Family Environment During Adolescence Predicts Marijuana Use and Antisocial Personality Disorder in Adulthood. J Child Fam Stud 25:661-668
Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2016) Pathways from victimization to substance use: Post traumatic stress disorder as a mediator. Psychiatry Res 237:153-8
Lee, Jung Yeon; Brook, Judith S; Nezia, Nasrat et al. (2016) Adolescent predictors of alcohol use in adulthood: A 22-year longitudinal study. Am J Addict 25:549-56
Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2016) Trajectories of Cigarette Smoking Beginning in Adolescence Predict Insomnia in the Mid Thirties. Subst Use Misuse 51:616-24
Brook, Judith S; Lee, Jung Yeon; Brook, David W (2015) Trajectories of Marijuana Use Beginning in Adolescence Predict Tobacco Dependence in Adulthood. Subst Abus 36:470-7
Brook, Judith S; Lee, Jung Yeon; Finch, Stephen J et al. (2015) Conjoint trajectories of depressive symptoms and delinquent behavior predicting substance use disorders. Addict Behav 42:14-9

Showing the most recent 10 out of 49 publications