This is a competing continuation application. This longitudinal study examines the etiologic determinants of changes between adolescence and adulthood in alcohol and drug use and dependence, and the consequences of alcohol and drug use and abuse/dependence on the individual's functioning. The ultimate goal of this research is to investigate developmental pathways to alcohol and drug use and dependence and cessation, and to identify adult protective factors that will offset risks for alcohol and drug use and dependence in adulthood. The sample includes low-income urban African American and Puerto Rican adults who were seen in early/middle adolescence, then in late adolescence, then in their early 20?s, and again in their mid 20?s. We now propose to study them in their thirties. A fifth data collection is proposed to accomplish the following: (1) examine the interrelations and interactions of risk and protective factors, including personality, family, peers, ecological context, acculturation/cultural values, and African American and Puerto Rican ethnic/racial identity, as they affect the course of alcohol and drug use/abuse/dependence (i.e., onset, stability, cessation) and criminal behavior in these adults;and (2) To study the consequences of early alcohol and drug use and abuse/dependence and other problem behaviors on adult intra- and interpersonal functioning. Interviews with the adult participants will be conducted by trained, interviewers. Scales with adequate psychometric properties measuring the independent variables will be developed from the interview schedules. The primary analytic techniques will be structural equation modeling and other regression-based techniques. This research will enable us to provide further information on (1) suggested specific strategies to prevent increases in alcohol and drug use and dependence, (2) factors promoting the decrease or cessation of drug use, and (3) the timing most adequate to implement these strategies.
The significance of the proposed study lies in its potential to identify important risk and protective factors for alcohol and drug use and dependence and their developmental timing. Thus, knowledge gained from this research will inform both prevention and public policy about the developmental pathways to alcohol and drug use and dependence, and factors related to cessation. In sum, the goals of this study should serve to provide information on specific strategies to prevent increases in alcohol and drug use and dependence, and on how and when these strategies can be most effectively implemented, which is of great relevance to the mission of the National Institute on Drug Abuse.
|Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2018) Trajectories of cannabis use beginning in adolescence associated with symptoms of posttraumatic stress disorder in the mid-thirties. Subst Abus 39:39-45|
|Lee, Jung Yeon; Brook, Judith S; De La Rosa, Mario et al. (2017) The association between alcohol use trajectories from adolescence to adulthood and cannabis use disorder in adulthood: a 22-year longitudinal study. Am J Drug Alcohol Abuse 43:727-733|
|Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2017) Joint trajectories of cigarette smoking and depressive symptoms from the mid-20s to the mid-30s predicting generalized anxiety disorder. J Addict Dis 36:158-166|
|Lee, Jung Yeon; Brook, Judith S; Pahl, Kerstin et al. (2017) Longitudinal pathways from unconventional personal attributes in the late 20s to cannabis use prior to sexual intercourse in the late 30s. Addict Behav 74:148-152|
|Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2016) An Adverse Family Environment During Adolescence Predicts Marijuana Use and Antisocial Personality Disorder in Adulthood. J Child Fam Stud 25:661-668|
|Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2016) Pathways from victimization to substance use: Post traumatic stress disorder as a mediator. Psychiatry Res 237:153-8|
|Lee, Jung Yeon; Brook, Judith S; Nezia, Nasrat et al. (2016) Adolescent predictors of alcohol use in adulthood: A 22-year longitudinal study. Am J Addict 25:549-56|
|Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2016) Trajectories of Cigarette Smoking Beginning in Adolescence Predict Insomnia in the Mid Thirties. Subst Use Misuse 51:616-24|
|Brook, Judith S; Lee, Jung Yeon; Finch, Stephen J et al. (2015) Conjoint trajectories of depressive symptoms and delinquent behavior predicting substance use disorders. Addict Behav 42:14-9|
|Lee, Jung Yeon; Brook, Judith S; Finch, Stephen J et al. (2015) Trajectories of marijuana use from adolescence to adulthood predicting unemployment in the mid 30s. Am J Addict 24:452-9|
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