Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA007610-05
Application #
2120093
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1992-03-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Arkansas for Medical Sciences
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Little Rock
State
AR
Country
United States
Zip Code
72205
White, Sarah J; Hendrickson, Howard P; Atchley, William T et al. (2014) Treatment with a monoclonal antibody against methamphetamine and amphetamine reduces maternal and fetal rat brain concentrations in late pregnancy. Drug Metab Dispos 42:1285-91
White, Sarah; Laurenzana, Elizabeth; Hendrickson, Howard et al. (2011) Gestation time-dependent pharmacokinetics of intravenous (+)-methamphetamine in rats. Drug Metab Dispos 39:1718-26
Owens, S Michael; Atchley, William T; Hambuchen, Michael D et al. (2011) Monoclonal antibodies as pharmacokinetic antagonists for the treatment of (+)-methamphetamine addiction. CNS Neurol Disord Drug Targets 10:892-8
Hubbard, Jonathan J; Laurenzana, Elizabeth M; Williams, D Keith et al. (2011) The fate and function of therapeutic antiaddiction monoclonal antibodies across the reproductive cycle of rats. J Pharmacol Exp Ther 336:414-22
Hubbard, J J; Laurenzana, E M; Williams, D K et al. (2011) Chronic anti-phencyclidine monoclonal antibody therapy decreases phencyclidine-induced in utero fetal mortality in pregnant rats. Int Immunopharmacol 11:2181-7
Chimalakonda, Krishna C; Hailey, Chris; Black, Ryan et al. (2010) Development and validation of an LC-MS/MS method for determination of phencyclidine in human serum and its application to human drug abuse cases. Anal Methods 2:1249-1254
Gentry, W B; Ruedi-Bettschen, D; Owens, S M (2010) Anti-(+)-methamphetamine monoclonal antibody antagonists designed to prevent the progression of human diseases of addiction. Clin Pharmacol Ther 88:390-3
White, Sarah J; Laurenzana, Elizabeth M; Gentry, William Brooks et al. (2009) Vulnerability to (+)-methamphetamine effects and the relationship to drug disposition in pregnant rats during chronic infusion. Toxicol Sci 111:27-36
Lacy, H Marie; Gunnell, Melinda G; Laurenzana, Elizabeth M et al. (2008) Engineering and characterization of a mouse/human chimeric anti-phencyclidine monoclonal antibody. Int Immunopharmacol 8:1-11
Naef, Lindsay; Srivastava, Lalit; Gratton, Alain et al. (2008) Maternal high fat diet during the perinatal period alters mesocorticolimbic dopamine in the adult rat offspring: reduction in the behavioral responses to repeated amphetamine administration. Psychopharmacology (Berl) 197:83-94

Showing the most recent 10 out of 27 publications