Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA008163-04
Application #
2120638
Study Section
Special Emphasis Panel (SRCD (06))
Project Start
1993-04-01
Project End
1997-09-29
Budget Start
1996-04-01
Budget End
1997-09-29
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
Organized Research Units
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Arttamangkul, Seksiri; Heinz, Daniel A; Bunzow, James R et al. (2018) Cellular tolerance at the µ-opioid receptor is phosphorylation dependent. Elife 7:
Levitt, Erica S; Williams, John T (2018) Desensitization and Tolerance of Mu Opioid Receptors on Pontine Kölliker-Fuse Neurons. Mol Pharmacol 93:8-13
Hunnicutt, Barbara J; Jongbloets, Bart C; Birdsong, William T et al. (2016) A comprehensive excitatory input map of the striatum reveals novel functional organization. Elife 5:
Arttamangkul, Seksiri; Birdsong, William; Williams, John T (2015) Does PKC activation increase the homologous desensitization of ? opioid receptors? Br J Pharmacol 172:583-92
Levitt, Erica S; Abdala, Ana P; Paton, Julian F R et al. (2015) ? opioid receptor activation hyperpolarizes respiratory-controlling Kölliker-Fuse neurons and suppresses post-inspiratory drive. J Physiol 593:4453-69
Birdsong, William T; Arttamangkul, Seksiri; Bunzow, James R et al. (2015) Agonist Binding and Desensitization of the ?-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain. Mol Pharmacol 88:816-24
Williams, John T (2014) Desensitization of functional µ-opioid receptors increases agonist off-rate. Mol Pharmacol 86:52-61
Birdsong, William T; Arttamangkul, Seksiri; Clark, Mary J et al. (2013) Increased agonist affinity at the ?-opioid receptor induced by prolonged agonist exposure. J Neurosci 33:4118-27
Banghart, Matthew R; Williams, John T; Shah, Ruchir C et al. (2013) Caged naloxone reveals opioid signaling deactivation kinetics. Mol Pharmacol 84:687-95
Arttamangkul, Seksiri; Lau, Elaine K; Lu, Hsin-Wei et al. (2012) Desensitization and trafficking of ýý-opioid receptors in locus ceruleus neurons: modulation by kinases. Mol Pharmacol 81:348-55

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