Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
1R01DA010035-01A1
Application #
2123491
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1996-09-01
Project End
2000-07-31
Budget Start
1996-09-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Maryland Baltimore
Department
Other Health Professions
Type
Schools of Pharmacy
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201

  Publications

Sinha, Bhaswati; Cao, Zhengyu; Murray, Thomas F et al. (2009) Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors. J Med Chem 52:7372-5
Dattachowdhury, Bhaswati; Murray, Thomas F; Aldrich, Jane V (2009) The synthesis of DAMGO-based potential affinity labels with high mu opioid receptor affinity and the formation of cyclic O-alkyl thiocarbamates. Adv Exp Med Biol 611:265-6
Aldrich, Jane V; Kumar, Vivek; Murray, Thomas F et al. (2009) Dual labeled peptides as tools to study receptors: nanomolar affinity derivatives of TIPP (Tyr-Tic-Phe-Phe) containing an affinity label and biotin as probes of delta opioid receptors. Bioconjug Chem 20:201-4
Aldrich, Jane V; Kumar, Vivek; Dattachowdhury, Bhaswati et al. (2008) Solid Phase Synthesis and Application of Labeled Peptide Derivatives: Probes of Receptor-Opioid Peptide Interactions. Int J Pept Res Ther 14:315-321
Aldrich, J V; Choi, H; Murray, T F (2004) An affinity label for delta-opioid receptors derived from [D-Ala2]deltorphin I. J Pept Res 63:108-15
Choi, H; Murray, T F; Aldrich, J V (2003) Synthesis and evaluation of potential affinity labels derived from endomorphin-2. J Pept Res 61:58-62
Kumar, Vivek; Aldrich, Jane V (2003) A solid-phase synthetic strategy for labeled peptides: synthesis of a biotinylated derivative of the delta opioid receptor antagonist TIPP (Tyr-Tic-Phe-Phe-OH). Org Lett 5:613-6
Choi, Heekyung; Murray, Thomas F; Aldrich, Jane V (2003) Synthesis and evaluation of derivatives of leucine enkephalin as potential affinity labels for delta opioid receptors. Biopolymers 71:552-7
Choi, H; Murray, T F; Aldrich, J V (2003) Dermorphin-based potential affinity labels for mu-opioid receptors. J Pept Res 61:40-5
Kumar, Vivek; Murray, Thomas F; Aldrich, Jane V (2002) Solid phase synthesis and evaluation of Tyr-Tic-Phe-Phe(p-NHCOCH(2)Br) ([Phe(p-bromoacetamide)(4)]TIPP), a potent affinity label for delta opioid receptors. J Med Chem 45:3820-3

Showing the most recent 10 out of 14 publications