Participation in needle exchange programs (NEPs) is associated with increased use of sterile syringes, reduction in high-risk drug injection behaviors, and lower incidence of HIV seroconversion. These settings can also operate as conduits to treatment centers dedicated to reducing drug use and risk of HIV and other infectious diseases. NEP participants have severe opioid dependence, yet many are ambivalent about entering treatment programs that emphasize reductions of drug use, and interest in treatment is hindered further by limited access to immediate treatment in many areas of the country. Our current NIDA grant (Community Based Intervention at Needle Exchange Sites) shows that a single motivational enhancement session increases the treatment seeking of needle exchangers. The proposed 5-year competing continuation study builds logically on our current work and on the research of others by integrating a number of proven interventions to promote the treatment enrollment of needle exchangers. An important new component of the intervention is a procedure for helping participants return to treatment following discharge. New needle exchange participants (n = 635) will be randomly assigned to one of three study conditions: 1) Motivated Referral Condition (MRC), 2) Motivated Referral Condition plus Incentives (MRC + Incentives), or 3) Standard Referral Condition (SRC). Participants assigned to MRC only condition will be referred to 8 motivational enhancement sessions to help encourage treatment interest, and to 16 treatment readiness groups to maintain motivation and provide information on finding treatment. Those referred to the MRC + Incentives condition will receive an identical referral procedure, and will be offered incentives for complying with each aspect of the referral process, and for entering treatment. SRC participants will receive updated lists of treatment programs admitting patients. All participants who leave treatment will be referred back to the BNEP. MRC and MRC + Incentives participants will be referred from the BNEP back to the treatment readiness group, while MRC + Incentives participants will also receive incentives for attending the group and re-entering treatment. SRC participants will not receive access to the treatment readiness group, nor will they receive incentives for treatment re-entry. All participants will be followed monthly for 16 months. The primary dependent measures are rates of drug abuse treatment enrollment and re-entry, speed of enrollment and re-entry, total days in treatment, use of community resources (including the BNEP), and self-reported rates of drug use and risky behavior. This study will continue our work by expanding and strengthening the impressive public health and therapeutic benefits already achieved by many needle exchange programs.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA012347-05
Application #
6661870
Study Section
Special Emphasis Panel (ZRG1-AARR-7 (01))
Program Officer
Hartsock, Peter
Project Start
1999-04-01
Project End
2007-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
5
Fiscal Year
2003
Total Cost
$633,847
Indirect Cost
Name
Johns Hopkins University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Kidorf, Michael; Brooner, Robert K; Leoutsakos, Jeannie-Marie et al. (2018) Treatment initiation strategies for syringe exchange referrals to methadone maintenance: A randomized clinical trial. Drug Alcohol Depend 187:343-350
Kidorf, Michael; Latkin, Carl; Brooner, Robert K (2016) Presence of Drug-Free Family and Friends in the Personal Social Networks of People Receiving Treatment for Opioid Use Disorder. J Subst Abuse Treat 70:87-92
Peirce, Jessica M; Schacht, Rebecca L; Brooner, Robert K et al. (2014) Prospective risk factors for traumatic event reexposure in community syringe exchange participants. Drug Alcohol Depend 138:98-102
Kidorf, Michael; King, Van L; Peirce, Jessica et al. (2013) An observation of lower rates of drug use over time in community syringe exchangers. Am J Addict 22:271-6
Peirce, Jessica M; Brooner, Robert K; Kolodner, Ken et al. (2013) Prospective effects of traumatic event re-exposure and post-traumatic stress disorder in syringe exchange participants. Addiction 108:146-53
Peirce, Jessica M; Kolodner, Ken; Brooner, Robert K et al. (2012) Traumatic event re-exposure in injecting drug users. J Urban Health 89:117-28
Kidorf, Michael; King, Van L; Gandotra, Neeraj et al. (2012) Improving treatment enrollment and re-enrollment rates of syringe exchangers: 12-month outcomes. Drug Alcohol Depend 124:162-6
Kidorf, Michael; King, Van L; Peirce, Jessica et al. (2011) A treatment reengagement intervention for syringe exchangers. J Subst Abuse Treat 41:415-21
Kidorf, Michael; King, Van L; Peirce, Jessica et al. (2011) Benefits of concurrent syringe exchange and substance abuse treatment participation. J Subst Abuse Treat 40:265-71
Kidorf, Michael; King, Van L; Peirce, Jessica et al. (2010) Psychiatric distress, risk behavior, and treatment enrollment among syringe exchange participants. Addict Behav 35:499-503

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