This application is for a 5-year continuation of the national longitudinal panel data collections of the Monitoring the Future (MTF) study, an ongoing epidemiological and etiological substance use research and reporting project begun in 1975. In addition to being a basic research study, MTF has become one of the nation's most relied upon sources of information on trends in illicit drug, alcohol, and tobacco use among American adolescents, college students, and adults. This MTF Panel application seeks to continue the follow-up surveys of high school graduates at modal ages 19?30, 35, 40, 45, 50, 55, and now 60. The companion Main grant covers in-school data collections, providing the nationally representative samples of 12th graders for follow up; it also covers data analysis. The Panel and Main components together comprise the integrated MTF study. MTF's broad measurement covers (a) initiation, use, and cessation for over 50 categories and sub-categories of licit and illicit drugs, including symptoms of substance use disorders; (b) attitudes and beliefs about substances, perceived availability, and peer norms; (c) individual risk and protective factors (e.g., depressive affect, pro-social activities); (d) aspects of key social contexts (e.g., home, work), and social role statuses and transitions; (e) health, social, and achievement consequences; and (f) risk and protective behaviors related to the spread of HIV/AIDS. The cohort-sequential longitudinal design permits the measurement and differentiation of three types of change?age, period, and cohort. Each has different determinants, and all three types of change have been shown by MTF to occur for most drugs. Factors that may explain historical trends and cohort differences are also monitored; additional factors come from other data that can be (and have been) combined with MTF data in collaborative efforts. MTF Panel is designed to document the developmental course and consequences of drug use and related attitudes from adolescence through adulthood (ages 18-60), and to determine the individual and contextual characteristics and social role transitions that affect use and related attitudes as well a broad array of adult consequences. Research on risk and protective behaviors for the transmission of HIV/AIDS will be continued and expanded to include adults aged 19-40. All of this work will be extended to new data collection years, cohorts, and ages under this application. Substance use among the nation's current college students and non-college youth will be tracked for another five years, totaling 40 years. The long-term follow-up data will now include age 60 surveys of cohorts who were in high school during historic peaks in teen substance use, especially important for understanding how earlier and ongoing substance use and abuse relates to declining health in middle to older adulthood. Impacts of policy changes will be evaluated, including state-level legalization of marijuana for recreational use. The investigators will complete current experiments on the utility of web-based follow-up survey methods and implement a remote data portal to allow access to MTF data by external researchers. Results will continue to elucidate drug use from adolescence through adulthood?including the use of new drugs and modalities?with important implications for national policy, research, prevention, and treatment agendas. As our nation progresses toward marijuana legalization and as electronic vaporizers gain popularity, the need to understand young through middle adult trends and consequences on health, well-being and work and family life has never been greater.

Public Health Relevance

This research project will continue the longitudinal study of smoking, drinking, and illicit drug use among nationally representative samples of high school graduates, as part of the ongoing integrated Monitoring the Future (MTF) study. This MTF Panel application covers five new longitudinal data collections in 2017/18 through 2021/22 from national samples of adults ages 19 through 60 from each high school graduating class since 1976. The purpose is to track patterns of substance use and HIV/AIDS risk and protective behaviors, to examine possible causes, correlates, and long-term consequences, and to differentiate three types of change?age, period, and cohort. During the next five years, knowledge gained from the MTF Panel study will increase our scientific understanding of substance use causes, correlates and consequences from adolescence through adulthood and inform prevention strategies and national and state drug use policies more generally. As our nation progresses toward marijuana legalization, the need to understand adult trends and consequences on health and well-being and work and family life has never been greater.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA016575-18
Application #
9880407
Study Section
Addiction Risks and Mechanisms Study Section (ARM)
Program Officer
Lopez, Marsha
Project Start
2003-09-30
Project End
2022-03-31
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
18
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Biostatistics & Other Math Sci
Type
Organized Research Units
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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McCabe, Sean Esteban; Veliz, Philip; Schulenberg, John E (2018) How Collegiate Fraternity and Sorority Involvement Relates to Substance Use During Young Adulthood and Substance Use Disorders in Early Midlife: A National Longitudinal Study. J Adolesc Health 62:S35-S43
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Bray, Bethany C; Dziak, John J; Patrick, Megan E et al. (2018) Inverse Propensity Score Weighting with a Latent Class Exposure: Estimating the Causal Effect of Reported Reasons for Alcohol Use on Problem Alcohol Use 16 Years Later. Prev Sci :
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Terry-McElrath, Yvonne M; Patrick, Megan E (2018) Simultaneous Alcohol and Marijuana Use Among Young Adult Drinkers: Age-Specific Changes in Prevalence from 1977 to 2016. Alcohol Clin Exp Res 42:2224-2233
Martz, Meghan E; Schulenberg, John E; Patrick, Megan E (2018) Passing on Pot: High School Seniors' Reasons for Not Using Marijuana as Predictors of Future Use. J Stud Alcohol Drugs 79:761-769

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