The overall goal of this study is an integrated understanding of the processing of sound by the two ears and the application of this understanding to improving the functional hearing abilities of people with hearing losses or neurological disorders. The auditory system is specialized to take advantage of the differences between the pressure signals at the two ears, and these differences are used to create a perceptual map of the acoustic environment. The best known reflections of this binaural processing are the localization of sound sources and the ability to listen to one talker in the presence of other talkers (the """"""""cocktail party effect""""""""). We believe that some of the difficulties experienced in noisy environments by listeners with hearing losses are related to an incomplete utilization of binaural differences, and a part of our study is directed toward testing the hypotheses with speech intelligibility experiments both in sound fields and using headphones.
The specific aims of the proposed work include: the development of computational models of binaurally sensitive neurons in the auditory brainstem and midbrain, psychophysical experimentation and modeling that relates psychophysical abilities to physiological responses, measurement of speech intelligibility and localization abilities in reverberant environments and in the presence of multiple sound sources, and the development of techniques for testing listeners with and without hearing aids in simulated complex environments.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
2R01DC000100-24A1
Application #
2766031
Study Section
Special Emphasis Panel (ZRG1-IFCN-6 (01))
Project Start
1988-04-01
Project End
2003-11-30
Budget Start
1998-12-01
Budget End
1999-11-30
Support Year
24
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Boston University
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
042250712
City
Boston
State
MA
Country
United States
Zip Code
02215
Best, Virginia; Mason, Christine R; Swaminathan, Jayaganesh et al. (2017) Use of a glimpsing model to understand the performance of listeners with and without hearing loss in spatialized speech mixtures. J Acoust Soc Am 141:81
Mi, Jing; Groll, Matti; Colburn, H Steven (2017) Comparison of a target-equalization-cancellation approach and a localization approach to source separation. J Acoust Soc Am 142:2933
Spencer, Nathaniel J; Hawley, Monica L; Colburn, H Steven (2016) Relating interaural difference sensitivities for several parameters measured in normal-hearing and hearing-impaired listeners. J Acoust Soc Am 140:1783
Mi, Jing; Colburn, H Steven (2016) A Binaural Grouping Model for Predicting Speech Intelligibility in Multitalker Environments. Trends Hear 20:
Dong, Junzi; Colburn, H Steven; Sen, Kamal (2016) Cortical Transformation of Spatial Processing for Solving the Cocktail Party Problem: A Computational Model(1,2,3). eNeuro 3:
Swaminathan, Jayaganesh; Mason, Christine R; Streeter, Timothy M et al. (2016) Role of Binaural Temporal Fine Structure and Envelope Cues in Cocktail-Party Listening. J Neurosci 36:8250-7
Chung, Yoojin; Delgutte, Bertrand; Colburn, H Steven (2015) Modeling binaural responses in the auditory brainstem to electric stimulation of the auditory nerve. J Assoc Res Otolaryngol 16:135-58
Wan, Rui; Durlach, Nathaniel I; Colburn, H Steven (2014) Application of a short-time version of the Equalization-Cancellation model to speech intelligibility experiments with speech maskers. J Acoust Soc Am 136:768-76
Wang, Le; Devore, Sasha; Delgutte, Bertrand et al. (2014) Dual sensitivity of inferior colliculus neurons to ITD in the envelopes of high-frequency sounds: experimental and modeling study. J Neurophysiol 111:164-81
Kidd Jr, Gerald; Mason, Christine R; Streeter, Timothy et al. (2013) Perceiving sequential dependencies in auditory streams. J Acoust Soc Am 134:1215-31

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