Stuttering is a disorder of speech with a prevalence estimated to be 1% of the world's population. It is often a significant communicative problem for the individual, limiting educational and employment opportunities and social and psychological adjustment. The etiology of stuttering is unknown, and treatment strategies and outcomes are highly variable. A major impediment to understanding the etiology of stuttering and to the development of successful therapeutic techniques is the lack of understanding of the physiological bases of the disorder. Stuttering manifests itself as a breakdown in speech motor processes. The complex factors known to affect the occurrence of stuttering, including psychosocial, cognitive, and linguistic variables, must ultimately have an effect on the physiological events necessary for the production of speech. Therefore, to understand stuttering it is essential to understand the physiological mechanisms underlying disruptions of speech motor processes in stuttering. The experiments proposed in this application addresses the role of linguistic processing in stuttering by taking a new approach, one that focuses on the neurophysiology of the perception and the production of linguistic stimuli. Averaged electrical responses of the brain to linguistic stimuli will be used to explore the linguistic processing abilities of children and adults who stutter. These experiments will determine if people who stutter have atypical neural subsystems for language even when they are only listening to words and not producing them. In another set of experiments the same participants will produce utterances that are designed to challenge linguistic planning and production processes for speech. The results of these experiments will provide major progress toward understanding the multiple factors that influence stuttering in children and adults.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000559-13
Application #
6624795
Study Section
Special Emphasis Panel (ZRG1-BBBP-7 (01))
Program Officer
Shekim, Lana O
Project Start
1988-12-01
Project End
2004-11-30
Budget Start
2002-12-01
Budget End
2003-11-30
Support Year
13
Fiscal Year
2003
Total Cost
$283,200
Indirect Cost
Name
Purdue University
Department
Other Health Professions
Type
Schools of Arts and Sciences
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Walsh, Bridget; Usler, Evan; Bostian, Anna et al. (2018) What Are Predictors for Persistence in Childhood Stuttering? Semin Speech Lang 39:299-312
Usler, Evan R; Walsh, Bridget (2018) The Effects of Syntactic Complexity and Sentence Length on the Speech Motor Control of School-Age Children Who Stutter. J Speech Lang Hear Res 61:2157-2167
Usler, Evan; Smith, Anne; Weber, Christine (2017) A Lag in Speech Motor Coordination During Sentence Production Is Associated With Stuttering Persistence in Young Children. J Speech Lang Hear Res 60:51-61
Kreidler, Kathryn; Hampton Wray, Amanda; Usler, Evan et al. (2017) Neural Indices of Semantic Processing in Early Childhood Distinguish Eventual Stuttering Persistence and Recovery. J Speech Lang Hear Res 60:3118-3134
Leech, Kathryn A; Bernstein Ratner, Nan; Brown, Barbara et al. (2017) Preliminary Evidence That Growth in Productive Language Differentiates Childhood Stuttering Persistence and Recovery. J Speech Lang Hear Res 60:3097-3109
Smith, Anne; Weber, Christine (2017) How Stuttering Develops: The Multifactorial Dynamic Pathways Theory. J Speech Lang Hear Res 60:2483-2505
Hilger, Allison I; Zelaznik, Howard; Smith, Anne (2016) Evidence That Bimanual Motor Timing Performance Is Not a Significant Factor in Developmental Stuttering. J Speech Lang Hear Res 59:674-85
Smith, Anne; Weber, Christine (2016) Childhood Stuttering: Where Are We and Where Are We Going? Semin Speech Lang 37:291-297
Walsh, Bridget; Mettel, Kathleen Marie; Smith, Anne (2015) Speech motor planning and execution deficits in early childhood stuttering. J Neurodev Disord 7:27
Usler, Evan; Weber-Fox, Christine (2015) Neurodevelopment for syntactic processing distinguishes childhood stuttering recovery versus persistence. J Neurodev Disord 7:4

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