Abstract

The long-term objective of this research is to optimize benefit from a cochlear implant for individual patients. Availability of new technology provides an opportunity to increase speech recognition for most patients, to develop a theory of parametric manipulation for optimized performance, and to improve poorer performers' speech recognition. In the proposed research, the large multidimensional, parametric space for electrostimulation is divided into the domains of speech processing parameters and fitting parameters.
Aim 1 evaluates the effects of changing speech processing parameters (electrode stimulation sites, number of channels, stimulation rate) on speech recognition.
Aim 2 evaluates the effects of four fitting parameters (maximum stimulation levels, electrode selection criteria, frequency boundary selection, compression functions) on speech recognition.
Aim 3 evaluates the relation between intracochlear electrode position, characteristic frequencies near the electrodes, and speech recognition to address sources of inter-subject variability in speech recognition.
Aim 4 monitors longitudinal performance and compares monopolar versus bipolar stimulation. The outcome of this research is intended to improve performance and clinical care of patients with multielectrode, intracochlear implants.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000581-10
Application #
6124966
Study Section
Hearing Research Study Section (HAR)
Program Officer
Donahue, Amy
Project Start
1989-12-01
Project End
2002-11-30
Budget Start
1999-12-01
Budget End
2000-11-30
Support Year
10
Fiscal Year
2000
Total Cost
$395,832
Indirect Cost

  Institution

Name
Washington University
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Long, Christopher J; Holden, Timothy A; McClelland, Gary H et al. (2014) Examining the electro-neural interface of cochlear implant users using psychophysics, CT scans, and speech understanding. J Assoc Res Otolaryngol 15:293-304
Holden, Laura K; Finley, Charles C; Firszt, Jill B et al. (2013) Factors affecting open-set word recognition in adults with cochlear implants. Ear Hear 34:342-60
Davidson, Lisa S; Geers, Ann E; Blamey, Peter J et al. (2011) Factors contributing to speech perception scores in long-term pediatric cochlear implant users. Ear Hear 32:19S-26S
Tobey, Emily A; Geers, Ann E; Sundarrajan, Madhu et al. (2011) Factors influencing speech production in elementary and high school-aged cochlear implant users. Ear Hear 32:27S-38S
Geers, Ann E; Sedey, Allison L (2011) Language and verbal reasoning skills in adolescents with 10 or more years of cochlear implant experience. Ear Hear 32:39S-48S
Moog, Jean S; Geers, Ann E; Gustus, Christine H et al. (2011) Psychosocial adjustment in adolescents who have used cochlear implants since preschool. Ear Hear 32:75S-83S
Geers, Ann E; Strube, Michael J; Tobey, Emily A et al. (2011) Epilogue: factors contributing to long-term outcomes of cochlear implantation in early childhood. Ear Hear 32:84S-92S
Meshik, Xenia; Holden, Timothy A; Chole, Richard A et al. (2010) Optimal cochlear implant insertion vectors. Otol Neurotol 31:58-63
Holstad, Beth A; Sonneveldt, Valerie G; Fears, Beverly T et al. (2009) Relation of electrically evoked compound action potential thresholds to behavioral T- and C-levels in children with cochlear implants. Ear Hear 30:115-27
Davidson, Lisa S; Skinner, Margaret W; Holstad, Beth A et al. (2009) The effect of instantaneous input dynamic range setting on the speech perception of children with the nucleus 24 implant. Ear Hear 30:340-9

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