Almost without exception, acquired language disorders resulting from focal brain injury are accompanied by impairments of verbal short-term memory (STM) and verbal learning. Moreover, disturbances in verbal STM are generally associated with language dysfunction, in some cases mild and not disruptive to most language activities. The co-occurrence of language and mnestic deficits in the aphasic population affords the opportunity to examine their relationships. The hypothesis that motivates this project is that word retrieval, verbal STM and verbal learning are three functions linked by processes that support the activation of linguistic representations. We propose to continue to explore these relationships in the study of language-impaired populations. The long-term goals of this project include (1) development of a computational model that integrates word retrieval, verbal short-term memory and the capacity for verbal learning and (2) application of this approach to the remediation of word retrieval disorders. A common theme of both theoretically- and treatment-oriented experiments is the examination of effects of phonological and semantic impairments on the performance of tasks that involve verbal STM and verbal learning. This approach will contribute to an understanding of the links between language processes and mnestic capacities that are engaged by the use of language materials.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC001924-08
Application #
6379317
Study Section
Special Emphasis Panel (ZRG1-CMS (02))
Program Officer
Cooper, Judith
Project Start
1993-12-01
Project End
2004-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
8
Fiscal Year
2001
Total Cost
$268,215
Indirect Cost
Name
Temple University
Department
Neurology
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Salis, Christos; Martin, Nadine; Meehan, Sarah V et al. (2018) Short-term memory span in aphasia: Insights from speech-timing measures. J Neurolinguistics 48:176-189
Martin, Nadine; Minkina, Irene; Kohen, Francine P et al. (2018) Assessment of linguistic and verbal short-term memory components of language abilities in aphasia. J Neurolinguistics 48:199-225
Minkina, Irene; Rosenberg, Samantha; Kalinyak-Fliszar, Michelene et al. (2017) Short-Term Memory and Aphasia: From Theory to Treatment. Semin Speech Lang 38:17-28
Peñaloza, Claudia; Mirman, Daniel; Tuomiranta, Leena et al. (2016) Novel word acquisition in aphasia: Facing the word-referent ambiguity of natural language learning contexts. Cortex 79:14-31
Peñaloza, Claudia; Benetello, Annalisa; Tuomiranta, Leena et al. (2015) Speech segmentation in aphasia. Aphasiology 29:724-743
Tuomiranta, Leena; Grönroos, Ann-Mari; Martin, Nadine et al. (2014) Vocabulary acquisition in aphasia: Modality can matter. J Neurolinguistics 32:42-58
Hula, William D; Fergadiotis, Gerasimos; Martin, Nadine (2012) Model choice and sample size in item response theory analysis of aphasia tests. Am J Speech Lang Pathol 21:S38-50
Laine, Matti; Martin, Nadine (2012) Cognitive Neuropsychology Has Been, Is, And Will Be Significant To Aphasiology. Aphasiology 26:1362-1376
Martin, Nadine; Kohen, Francine; Kalinyak-Fliszar, Michelene et al. (2012) Effects of working memory load on processing of sounds and meanings of words in aphasia. Aphasiology 26:462-493
Kalinyak-Fliszar, Michelene; Kohen, Francine; Martin, Nadine (2011) Remediation of language processing in aphasia: Improving activation and maintenance of linguistic representations in (verbal) short-term memory. Aphasiology 25:1095-1131

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