Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC002873-02
Application #
2128389
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1995-06-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
McCann, Jessica R; Mason, Stanley N; Auten, Richard L et al. (2016) Early-Life Intranasal Colonization with Nontypeable Haemophilus influenzae Exacerbates Juvenile Airway Disease in Mice. Infect Immun 84:2022-2030
Mell, Joshua Chang; Viadas, Cristina; Moleres, Javier et al. (2016) Transformed Recombinant Enrichment Profiling Rapidly Identifies HMW1 as an Intracellular Invasion Locus in Haemophilus influenza. PLoS Pathog 12:e1005576
Rempe, Katherine A; Porsch, Eric A; Wilson, Jolaine M et al. (2016) The HMW1 and HMW2 Adhesins Enhance the Ability of Nontypeable Haemophilus influenzae To Colonize the Upper Respiratory Tract of Rhesus Macaques. Infect Immun 84:2771-8
Rempe, Katherine A; Spruce, Lynn A; Porsch, Eric A et al. (2015) Unconventional N-Linked Glycosylation Promotes Trimeric Autotransporter Function in Kingella kingae and Aggregatibacter aphrophilus. MBio 6:
Grass, Susan; Rempe, Katherine A; St Geme 3rd, Joseph W (2015) Structural determinants of the interaction between the TpsA and TpsB proteins in the Haemophilus influenzae HMW1 two-partner secretion system. J Bacteriol 197:1769-80
McCann, Jessica R; St Geme 3rd, Joseph W (2014) The HMW1C-like glycosyltransferases--an enzyme family with a sweet tooth for simple sugars. PLoS Pathog 10:e1003977
Spahich, Nicole A; St Geme 3rd, Joseph W (2011) Structure and Function of the Haemophilus influenzae Autotransporters. Front Cell Infect Microbiol 1:5
Kawai, Fumihiro; Grass, Susan; Kim, Youngchang et al. (2011) Structural insights into the glycosyltransferase activity of the Actinobacillus pleuropneumoniae HMW1C-like protein. J Biol Chem 286:38546-57
Choi, Kyoung-Jae; Grass, Susan; Paek, Seonghee et al. (2010) The Actinobacillus pleuropneumoniae HMW1C-like glycosyltransferase mediates N-linked glycosylation of the Haemophilus influenzae HMW1 adhesin. PLoS One 5:e15888
Grass, Susan; Lichti, Cheryl F; Townsend, R Reid et al. (2010) The Haemophilus influenzae HMW1C protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin. PLoS Pathog 6:e1000919

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