The long-term goal of this research is to improve cochlear implant patient performance by maximizing both the transmission and reception of acoustic patterns. We hypothesize that, due to the loss of fine spectral details, cochlear implant patients have great difficulty in challenging listening conditions (e.g., noise, competing speech, reverberation, unfamiliar talkers, etc.). We propose to optimize the input acoustic signal in response to the acoustic environment, or to different speaker characteristics, thereby improving the transmission of speech patterns. We further hypothesize that poor patient performance may be partly due to sub-optimal settings of important speech processor parameters (e.g., stimulation mode, frequency allocation, stimulation rate, etc.). We propose to optimize these parameters according to individual patients' psychophysical capabilities, thereby improving the reception of speech patterns. Combining these two approaches - pre-processing the input signal and optimizing processor parameters - will provide the greatest benefit to patient performance for a variety of listening conditions. There are three specific aims in the proposed research.
Specific aim 1 is to improve the transmission of acoustic patterns. We will evaluate novel speech enhancement algorithms that optimize the input acustic patterns in response to the acoustic environment, or to different speaker characteristics.
Specific aim 2 is to improve the reception of acoustic patterns. We will explore the perceptual space for important speech processor parameters and optimize these parameters according to individual patients' psychophysical capabilities.
Specific aim 3 is to evaluate the long-term effects of changes to speech processing. While we will generally study the effects of each optimization technique independently in each experiment, the techniques can be easily combined to further optimize audio processing for cochlear implants, once the parameter space is defined. Each of the proposed strategies seeks to optimize some aspect of speech processing and, when combined, the benefit from one strategy may be directly enhanced by the benefit from another. This synergy may further improve patient performance for a wide variety of listening conditions. The proposed research is of great clinical importance in terms of maximizing patient performance under a variety of listening conditions. It is also of great theoretical interest in terms of understanding the neural and perceptual mechanisms involved in pattern recognition. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
2R01DC004993-06A1
Application #
7260030
Study Section
Language and Communication Study Section (LCOM)
Program Officer
Miller, Roger
Project Start
2001-07-01
Project End
2012-04-30
Budget Start
2007-05-15
Budget End
2008-04-30
Support Year
6
Fiscal Year
2007
Total Cost
$373,844
Indirect Cost
Name
House Research Institute
Department
Type
DUNS #
062076989
City
Los Angeles
State
CA
Country
United States
Zip Code
90057
Cheng, Xiaoting; Liu, Yangwenyi; Shu, Yilai et al. (2018) Music Training Can Improve Music and Speech Perception in Pediatric Mandarin-Speaking Cochlear Implant Users. Trends Hear 22:2331216518759214
Stelmach, Julia; Landsberger, David M; Padilla, Monica et al. (2017) Determining the minimum number of electrodes that need to be pitch matched to accurately estimate pitch matches across the array. Int J Audiol 56:894-899
Liu, Yang-Wenyi; Tao, Duo-Duo; Jiang, Ye et al. (2017) Effect of spatial separation and noise type on sentence recognition by Mandarin-speaking cochlear implant users. Acta Otolaryngol 137:829-836
Tao, Duo-Duo; Fu, Qian-Jie; Galvin 3rd, John J et al. (2017) The development and validation of the Closed-set Mandarin Sentence (CMS) test. Speech Commun 92:125-131
Li, Yongxin; Wang, Shuncheng; Su, Qiaodang et al. (2017) Validation of list equivalency for Mandarin speech materials to use with cochlear implant listeners. Int J Audiol 56:S31-S40
Zhou, Xiaoqing; Li, Huajun; Galvin 3rd, John J et al. (2017) Effects of insertion depth on spatial speech perception in noise for simulations of cochlear implants and single-sided deafness. Int J Audiol 56:S41-S48
Su, Qiaotong; Galvin, John J; Zhang, Guoping et al. (2016) Effects of Within-Talker Variability on Speech Intelligibility in Mandarin-Speaking Adult and Pediatric Cochlear Implant Patients. Trends Hear 20:
Aronoff, Justin M; Stelmach, Julia; Padilla, Monica et al. (2016) Interleaved Processors Improve Cochlear Implant Patients' Spectral Resolution. Ear Hear 37:e85-90
Galvin 3rd, John J; Oba, Sandra I; Ba?kent, Deniz et al. (2015) Envelope Interactions in Multi-Channel Amplitude Modulation Frequency Discrimination by Cochlear Implant Users. PLoS One 10:e0139546
Yoon, Yang-Soo; Shin, You-Ree; Gho, Jae-Sook et al. (2015) Bimodal benefit depends on the performance difference between a cochlear implant and a hearing aid. Cochlear Implants Int 16:159-67

Showing the most recent 10 out of 64 publications