The research program developed in the proposal aims to understand how auditory cognition, in general, and speech perception, in particular, is mediated by cortical structures. Two broad questions are addressed. First, what is the functional neuroanatomy of speech sound processing? Second, are there cortical time-based mechanisms that provide a logistical basis for the analysis of auditory signals? These two questions are addressed in a series of magnetoencephalography (MEG) studies. Both research goals build on recent findings, primarily from neuroscience and cognitive neuroscience that suggest a new perspective on the functional anatomy and physiology of speech sound processing. Results from hemodynamic imaging studies (PET, fMRI) as well as electromagnetic recording techniques (EEG, MEG) show that the functional neuroanatomy of speech perception (i) is more bilaterally organized than previously assumed and (ii) that auditory areas in the temporal lobe play a core role, but that parietal and frontal areas are critically implicated in specific aspects of speech sound processing as well. Furthermore, neurophysiological results, both at the single-unit and systems levels, point to the importance of timing mechanisms in the representation and processing of auditory signals. Because MEG is a non-invasive recording technique that has the necessary temporal resolution (ms) to study neurophysiological timing phenomena and can also localize the activity in a useful anatomic context, it is the appropriate tool to address both broader questions.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
1R01DC005660-01
Application #
6513951
Study Section
Biobehavioral and Behavioral Processes 3 (BBBP)
Program Officer
Luethke, Lynn E
Project Start
2002-08-01
Project End
2007-07-31
Budget Start
2002-08-01
Budget End
2003-07-31
Support Year
1
Fiscal Year
2002
Total Cost
$468,025
Indirect Cost
Name
University of Maryland College Park
Department
Miscellaneous
Type
Schools of Arts and Sciences
DUNS #
City
College Park
State
MD
Country
United States
Zip Code
20742
Gwilliams, Laura; Linzen, Tal; Poeppel, David et al. (2018) In Spoken Word Recognition, the Future Predicts the Past. J Neurosci 38:7585-7599
Getz, Heidi; Ding, Nai; Newport, Elissa L et al. (2018) Cortical tracking of constituent structure in language acquisition. Cognition 181:135-140
Teng, Xiangbin; Tian, Xing; Doelling, Keith et al. (2018) Theta band oscillations reflect more than entrainment: behavioral and neural evidence demonstrates an active chunking process. Eur J Neurosci 48:2770-2782
Dikker, Suzanne; Wan, Lu; Davidesco, Ido et al. (2017) Brain-to-Brain Synchrony Tracks Real-World Dynamic Group Interactions in the Classroom. Curr Biol 27:1375-1380
Tal, Idan; Large, Edward W; Rabinovitch, Eshed et al. (2017) Neural Entrainment to the Beat: The ""Missing-Pulse"" Phenomenon. J Neurosci 37:6331-6341
Teng, Xiangbin; Tian, Xing; Rowland, Jess et al. (2017) Concurrent temporal channels for auditory processing: Oscillatory neural entrainment reveals segregation of function at different scales. PLoS Biol 15:e2000812
Ding, Nai; Melloni, Lucia; Yang, Aotian et al. (2017) Characterizing Neural Entrainment to Hierarchical Linguistic Units using Electroencephalography (EEG). Front Hum Neurosci 11:481
Ten Oever, Sanne; Schroeder, Charles E; Poeppel, David et al. (2017) Low-Frequency Cortical Oscillations Entrain to Subthreshold Rhythmic Auditory Stimuli. J Neurosci 37:4903-4912
Krakauer, John W; Ghazanfar, Asif A; Gomez-Marin, Alex et al. (2017) Neuroscience Needs Behavior: Correcting a Reductionist Bias. Neuron 93:480-490
Ding, Nai; Melloni, Lucia; Tian, Xing et al. (2017) Rule-based and Word-level Statistics-based Processing of Language: Insights from Neuroscience. Lang Cogn Neurosci 32:570-575

Showing the most recent 10 out of 104 publications